Protein Alignment HHEX and HOXA6

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_076919.1
• Gene: HOXA6 / 3203
• HGNCID: 5107
• Length: 233
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 61/230 - (26%)
• Similarity: 89/230 - (38%)
• Gaps: 46/230 - (20%)

  Fly    60 GSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQV--- 121
            |..:..|.|:...|:::.|.:..:....     ..|::|||..    ...|...||.||...
Human    31 GYDALRPFPASYGASSLPDKTYTSPCFY-----QQSNSVLACN----RASYEYGASCFYSDKDLS 86

  Fly   122 ------LQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCN-A 179
                  ...|:.|..:: ||...              .||.|.:...:|.......|...|.: .
Human    87 GASPSGSGKQRGPGDYL-HFSPE--------------QQYKPDSSSGQGKALHDEGADRKYTSPV 136

  Fly   180 YP--------AASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDR 236
            ||        |.:.|.|:   .|:|.| .:|..||..||..|..::||:...|..:|..|.||:|
Human   137 YPWMQRMNSCAGAVYGSH---GRRGRQ-TYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTER 197

  Fly   237 QVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVG 271
            |:|.||||||.||::.|....|....|..:.|..|
Human   198 QIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/50 (48%)
HOXA6	NP_076919.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..127		8/52 (15%)
		Antp-type hexapeptide	136..141		2/4 (50%)
		Homeodomain	156..212	CDD:459649	27/56 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..233		5/19 (26%)