Protein Alignment HHEX and HOXA5

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 61/253 - (24%)
• Similarity: 95/253 - (37%)
• Gaps: 54/253 - (21%)

  Fly    20 QKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASL-ATGSSSAAPTPSPSSATNIYDLSREA 83
            :..|.|.....|..|.:..|..|.       |.|:.|. ||.:.|..|.|.|.||
Human    58 RSGSGHFGSGERARSYAASASAAP-------AEPRYSQPATSTHSPQPDPLPCSA---------- 105

  Fly    84 AAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQP 148
                                     :.|.|.|..:........|.|.......:..:::...|..
Human   106 -------------------------VAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGT 145

  Fly   149 TAYCDQYSPFTMD---CEGFPNPASAAAALYCNAYP-AASFYMSN---FGVKRKGGQIRFTSQQT 206
            .:..::.:|.:.:   .:..|:||..|..   ..|| ....::|:   .|.:.|..:..:|..||
Human   146 ASGAEEDAPASSEQASAQSEPSPAPPAQP---QIYPWMRKLHISHDNIGGPEGKRARTAYTRYQT 207

  Fly   207 KNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRAN-LSKRSASAQG 263
            ..||..|..::||:...|..:|..|.|::||:|.||||||.||::.| |...|.:|.|
Human   208 LELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAG 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/50 (46%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		24/144 (17%)
		Antp-type hexapeptide	176..181		2/4 (50%)
		Homeodomain	196..252	CDD:459649	24/55 (44%)