Protein Alignment HHEX and HMX2

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_005510.1
• Gene: HMX2 / 3167
• HGNCID: 5018
• Length: 273
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 54/183 - (29%)
• Similarity: 72/183 - (39%)
• Gaps: 50/183 - (27%)

  Fly   148 PTAYC-DQYS----------PFTMDCEGFPNPASAAAALYCNAYPAASFYMSNF----------- 190
            |..:| ||:.          |....|.|.|..:..:........|..|...|:|
Human    63 PACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAG 127

  Fly   191 ------------GVKRKGGQIR------FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQ 237
                        |.:|:.|..:      |:..|...||:.|...:|||..||..||..|:||:.|
Human   128 SPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQ 192

  Fly   238 VKTWFQNRRAKWRR--------ANLSKRSASAQGPIAGAAVGSPSSASSSSVP 282
            |||||||||.||:|        ||::  .||||..::...|...||.....||
Human   193 VKTWFQNRRNKWKRQLSAELEAANMA--HASAQTLVSMPLVFRDSSLLRVPVP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	27/56 (48%)
HMX2	NP_005510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		15/88 (17%)
		Homeodomain	150..206	CDD:459649	27/55 (49%)