Protein Alignment HHEX and nkx2.5

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_571496.2
• Gene: nkx2.5 / 30696
• ZFINID: ZDB-GENE-980526-321
• Length: 314
• Species: Danio rerio
• Alignment Length: 254
• Identity: 70/254 - (27%)
• Similarity: 98/254 - (38%)
• Gaps: 54/254 - (21%)

  Fly    63 SAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSS----AVLAPTSLRFNPIY--------PDPAS 115
            |:..|.:|.|..:|.:|.:.    |..|.|:|.|    :.|.|||......:        |..:|
Zfish     5 SSQMTSTPFSVRDILNLEQN----QEDMVSLDMSQRLDSALIPTSSCMLSTFKQEQFMEMPSGSS 65

  Fly   116 LFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMD--------CEGFPNPASAA 172
            ||.:. ||..|...:...:|.|:...|...::.....|..:..|.:        |
Zfish    66 LFSED-LQEDKGNKINSINFSASGFYAKNFLEMDYVKDAKTDDTFEDKEKKDIGC---------- 119

  Fly   173 AALYCNAYPAASFYMSNF----GVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKL 233
                |...|.....:.:.    ..||:..::.|:..|...||.||...||||..||.|||..|||
Zfish   120 ----CQEDPGEDLKLDDAERPKQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKL 180

  Fly   234 TDRQVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSRC 292
            |..|||.||||||.|.:|....:       .:....:..|...   ||||| :..|..|
Zfish   181 TSTQVKIWFQNRRYKCKRQRQDQ-------TLEMVGIAPPRRI---SVPVL-VRDGKPC 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	29/50 (58%)
nkx2.5	NP_571496.2	Homeodomain	142..198	CDD:459649	29/55 (53%)