Protein Alignment HHEX and Alx4

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001100023.1
• Gene: Alx4 / 296511
• RGDID: 1310201
• Length: 399
• Species: Rattus norvegicus
• Alignment Length: 352
• Identity: 85/352 - (24%)
• Similarity: 112/352 - (31%)
• Gaps: 111/352 - (31%)

  Fly    27 SQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMK 91
            ||||.|||                  |......|....  |...|:|............|:|...
  Rat    25 SQSREGSS------------------PFRGFPGGDKFG--TTFLSAAAKGQGFGDAKGRARYGAG 69

  Fly    92 SMDSSAVL---APTSLRFNPIYPD-------------PASLFYQQ---------VLQLQK----- 126
            ..|.:|.|   |.....||...|.             ||.|:.|:         .|:||:
  Rat    70 QQDLAAPLESNAGARGSFNKFQPQPPTPQPPPAPPAPPAHLYLQRGACKTPPDGSLKLQEGSGGH 134

  Fly   127 NPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCE-------GFPNPASAAAALYCNAYPAAS 184
            |.:|.:|.:...:......:.|.:     .|..||..       |...|...|.|...:......
  Rat   135 NAALQVPCYAKESNLGEPELPPDS-----EPVGMDNSYLSVKETGAKGPQDRAGAEIPSPLEKTD 194

  Fly   185 FYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKW 249
            ...|. |.||: .:..|||.|.:.||..|..:.|.....|..||::..||:.:|:.|||||||||
  Rat   195 SESSK-GKKRR-NRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKW 257

  Fly   250 R-----------RANLS-----------KRSASAQGP--IAGAAVGSP----------------- 273
            |           |.:.|           :..|..|.|  |......||
  Rat   258 RKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWIGNNGAASPVPACVVPCDPVPACMSP 322

  Fly   274 ------SSASSSSVPVLNLGSGSRCGQ 294
                  |.|||.|..:...|:||..||
  Rat   323 HAHPPGSGASSVSDFLSVSGAGSHVGQ 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/61 (39%)
Alx4	NP_001100023.1	Homeodomain	203..259	CDD:459649	24/56 (43%)
		OAR	375..393	CDD:461067