Protein Alignment HHEX and Hoxd1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001099354.1
• Gene: Hoxd1 / 288151
• RGDID: 1309179
• Length: 328
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 86/317 - (27%)
• Similarity: 119/317 - (37%)
• Gaps: 88/317 - (27%)

  Fly    45 ATPHALAMPKASLATGS---------SSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSS--AV 98
            |.|.|| .|...|.:|.         ::|.|||||..|. ......:.||::||..:::.:  ..
  Rat    35 ARPVAL-QPAFPLGSGDGAFVSCLPLAAARPTPSPPVAP-AQPPGPQPAASRYAPCTLEGAYERG 97

  Fly    99 LAPTS------LRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAV---------------AA 142
            .||.|      |...|.:..|.:|.....   ...|.:   |:..:||               ||
  Rat    98 AAPASAAEYGFLGSGPAFDFPGALGRAAD---DSGPHV---HYATSAVFSSGGSFLLSGQVDFAA 156

  Fly   143 AAAVQPTAYC------------DQYSPFTMDCEGFPNPASAAAALYCNAYPAA------------ 183
            .|...|...|            ...||....|   |.|||..:.|     |||
  Rat   157 FAEPGPFPACLKEPADGHPGPFQTVSPAPGAC---PKPASPTSGL-----PAAHSTFEWMKVKRN 213

  Fly   184 ---SFYMSNFGVKRKGGQIR--FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQ 243
               ...:|.:|.......||  |:::|...||..|..:|||:...|..:|..|:|.|.|||.|||
  Rat   214 APKKSKLSEYGATSPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRMEIANCLQLNDTQVKIWFQ 278

  Fly   244 NRRAKWRRANLSKRSASAQGPIAGAA-VGSPSSASSSSVPV---LNLGSGSRCGQQS 296
            |||.|       ::....:|.:|.|| |.|.....|.:.|:   .||||.|:..:.|
  Rat   279 NRRMK-------QKKREREGLLATAASVASLQLPGSETSPIKSGRNLGSPSQAQEPS 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/52 (46%)
Hoxd1	NP_001099354.1	COG5576	<208..325	CDD:227863	40/123 (33%)
		Homeodomain	233..286	CDD:459649	24/59 (41%)