Protein Alignment HHEX and ALX3

DIOPT Version :9

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 64/263 - (24%)
• Similarity: 102/263 - (38%)
• Gaps: 42/263 - (15%)

  Fly    53 PKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRF------NPIYP 111
            |...:|:|.....|..:|::|.:::                 .:....|...||      .|..|
Human    15 PGPYVASGDEPPGPQGTPAAAPHLH-----------------PAPPRGPRLTRFPACGPLEPYLP 62

  Fly   112 DPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFP---------N 167
            :||....:.:..|...|:|...||..   ..|.|.:.|:....:....:||.|.|         :
Human    63 EPAKPPAKYLQDLGPGPALNGGHFYE---GPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGS 124

  Fly   168 PASAAAALYCNAYPAA--SFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQ 230
            |....|:|:....|..  |..::....|::..:..|::.|.:.||..|..:.|.....|..|||:
Human   125 PGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALR 189

  Fly   231 LKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPVLNL-----GSGS 290
            ..||:.:|:.||||||||||:.....:....:.|...|...|....:.|...:.|.     ||||
Human   190 TDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGS 254

  Fly   291 RCG 293
            ..|
Human   255 PGG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeobox	200..250	CDD:278475	21/49 (43%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		21/108 (19%)
		PRK12323	<13..131	CDD:237057	26/135 (19%)
		Homeobox	157..210	CDD:365835	22/52 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910