Protein Alignment HHEX and Dbx2

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_997416.2
• Gene: Dbx2 / 223843
• MGIID: 107445
• Length: 377
• Species: Mus musculus
• Alignment Length: 313
• Identity: 77/313 - (24%)
• Similarity: 109/313 - (34%)
• Gaps: 93/313 - (29%)

  Fly    18 LEQKSSSHRSQSRRGSSQSPVAVTA---------------GIATPHALAMPKASL-------ATG 60
            |..::.|.|...:|..:..|.||.|               |:..|...::.|:.|       ..|
Mouse    47 LSLRTRSPRLPGQRARTMLPSAVAAQAGAYWDVVASSALFGLPAPGFGSLGKSFLIENLLRAGAG 111

  Fly    61 SSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLR-----------------FNP 108
            .:.|.|.|.|:.......| |...|:...:|...:    .|..:|                 |.|
Mouse   112 PTHAPPPPRPAPGPECPQL-RPLPASPVPLKLCPA----GPFGVRWAFQMPPGRAPGERDSAFQP 171

  Fly   109 IYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAA--AVQPTAYCDQYSPFTMDCEGFPNPASA 171
            ..|.|:..|.           |..|.|.:|....:.  ...|||       |:.:..|.|
Mouse   172 SAPVPSKPFL-----------LSAPPFYSACCGGSCRRPASPTA-------FSREEHGLP----- 213

  Fly   172 AAALYCNAYPAASFYMSNFGVKRKGGQIR---FTSQQTKNLEARFASSKYLSPEERRHLALQLKL 233
                         ....:...|.:.|.:|   |:.:|.|.||..|...||:|..:||.||:.|.|
Mouse   214 -------------LLTQDSNSKARRGILRRAVFSEEQRKALEKMFQKQKYISKTDRRKLAVSLGL 265

  Fly   234 TDRQVKTWFQNRRAKWRRAN----LSKRS----ASAQGPIAGAAVGSPSSASS 278
            .:.|||.||||||.|||.:.    ||.|.    :..:..:|..|||.|....|
Mouse   266 KESQVKIWFQNRRMKWRNSKEKEVLSSRCLQEVSLQEDRLARPAVGCPPQCPS 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	27/53 (51%)
Dbx2	NP_997416.2	COG5576	<217..334	CDD:227863	39/102 (38%)
		Homeodomain	229..283	CDD:459649	27/53 (51%)