Protein Alignment HHEX and tab-1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_495392.1
• Gene: tab-1 / 185156
• WormBaseID: WBGene00006380
• Length: 197
• Species: Caenorhabditis elegans
• Alignment Length: 255
• Identity: 59/255 - (23%)
• Similarity: 102/255 - (40%)
• Gaps: 96/255 - (37%)

  Fly    10 AAFSIENI-------------LEQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGS 61
            ::|||:::             |:|.|.:.:|.|..||.:|.::|         :::|..:..|
 Worm     6 SSFSIDDLLRGHSNEIQRILKLDQTSPTPQSSSDEGSEKSSISV---------MSVPLTNELT-- 59

  Fly    62 SSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQK 126
                ||.:|:.:..::     .|||.:   .::.|.:||    :.|.::|.    |:....|::.
 Worm    60 ----PTITPALSDQLW-----LAAAAF---PIEHSLLLA----QRNGVFPG----FWSTADQIRL 104

  Fly   127 NPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFG 191
            :.:                      ...|....::|.
 Worm   105 SNA----------------------TKAYRRLRLECS---------------------------- 119

  Fly   192 VKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR 251
             :||...: |:.||.:.||.||.|.:|||..||..||..|.|::.||||||||||.|.::
 Worm   120 -RRKARTV-FSDQQLQGLERRFESQRYLSTPERIELANALNLSETQVKTWFQNRRMKHKK 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	28/50 (56%)
tab-1	NP_495392.1	Homeodomain	121..177	CDD:459649	30/56 (54%)