Protein Alignment HHEX and mls-2

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_508815.2
• Gene: mls-2 / 180751
• WormBaseID: WBGene00003377
• Length: 341
• Species: Caenorhabditis elegans
• Alignment Length: 333
• Identity: 74/333 - (22%)
• Similarity: 114/333 - (34%)
• Gaps: 116/333 - (34%)

  Fly    52 MPKASLATGSSSAAPTPSPSSAT--NIYDL----SREAAAAQYAMKSMDSSAVLAPTSLRFNPIY 110
            :||..|..........||..:..  ||.:|    .:....:..:..|.||:..:..|:..||
 Worm    27 LPKIELMEEEEEEEMKPSSDNKIKFNISELLEDDRKPTTQSSPSASSEDSTNEIEQTAFNFN--- 88

  Fly   111 PDPASLFYQQVLQLQK------------NPSLFMPHFQAAAVAAAAAVQPTAYCDQY-------- 155
            .||.......:||||:            :|....|.|..          |||....:
 Worm    89 FDPKMNPISALLQLQQTFLNVGNQQNMISPLTMFPFFGL----------PTAQLMHFKNMSNPDV 143

  Fly   156 ---------------------------SPFTMDCE-------GFPNPASAAAALYCNAYPAASFY 186
                                       ||...|.|       |..:.|:::.       |:.:
 Worm   144 NIQSDNGEEKDEKSEGKDGETRDSTGGSPLESDAEDDDDIGRGSDDEANSSD-------PSQN-- 199

  Fly   187 MSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR 251
                  ::|..:..|:..|...||..|...:|||.:||.:||.:|.||:.|||.||||||.|::|
 Worm   200 ------RKKKTRTVFSRSQVSQLEMMFECKRYLSSQERSNLAQKLHLTETQVKIWFQNRRNKFKR 258

  Fly   252 ------ANLSKR-----------SASAQGPI-------AGA----AVGSPSSASSSSVPVLNLGS 288
                  .|:|.:           :.:...||       ||.    .:.||..||:::......|.
 Worm   259 QAQTDDTNISLQMHRANVFSIPATTALTSPILTIPTTSAGVNMRNMISSPMDASATAAARFLFGF 323

  Fly   289 GSRCGQQS 296
            |:...||:
 Worm   324 GTLQAQQN 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	25/50 (50%)
mls-2	NP_508815.2	Homeodomain	202..258	CDD:459649	26/55 (47%)