Protein Alignment HHEX and mab-5

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_498695.1
• Gene: mab-5 / 176091
• WormBaseID: WBGene00003102
• Length: 200
• Species: Caenorhabditis elegans
• Alignment Length: 283
• Identity: 71/283 - (25%)
• Similarity: 95/283 - (33%)
• Gaps: 130/283 - (45%)

  Fly    60 GSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLR----FNPIYPDPASLFYQQ 120
            |:.:.|.:.|.||.|:....|..||||             |..:|:    :|..|.:.
 Worm    16 GAGTTASSQSASSGTSASASSSAAAAA-------------AANNLKTYELYNHTYMNN------- 60

  Fly   121 VLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYS-PFTMDCEGFPNPASAAAALYCNAYPAAS 184
                       |.|..||           .:.|..| ||..      ||..|.:|
 Worm    61 -----------MKHMLAA-----------GWMDNSSNPFAY------NPLQATSA---------- 87

  Fly   185 FYMSNFGVKR-------------------KGGQIRFTSQ-----QTKNLEARFASSKYLSPEERR 225
                |||..|                   |||:.:.|.|     ||..||..|...|||:.:.|:
 Worm    88 ----NFGETRTSMPAISQPVFPWMKMGGAKGGESKRTRQTYSRSQTLELEKEFHYHKYLTRKRRQ 148

  Fly   226 HLALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPVLNLGSGS 290
            .::..|.||:||||.||||||.|      .|:.|..:|                         ||
 Worm   149 EISETLHLTERQVKIWFQNRRMK------HKKEAKGEG-------------------------GS 182

  Fly   291 RCGQQSDEEDRMYLSEDDEDDDE 313
               .:||||     |..||.:::
 Worm   183 ---NESDEE-----SNQDEQNEQ 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	25/55 (45%)
mab-5	NP_498695.1	Homeodomain	118..174	CDD:459649	25/61 (41%)