Protein Alignment HHEX and cog-1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001022264.1
• Gene: cog-1 / 175149
• WormBaseID: WBGene00000584
• Length: 256
• Species: Caenorhabditis elegans
• Alignment Length: 309
• Identity: 77/309 - (24%)
• Similarity: 113/309 - (36%)
• Gaps: 94/309 - (30%)

  Fly     2 DIATKSSKAAFSIEN-ILEQKSSSHRSQSRRGSS--------QSPVAVTAGIATPHALAMPKASL 57
            |:..:...:.:||.| :||:|.||....|....|        :||.|.::.|..|
 Worm    18 DVENRKHSSTYSISNLLLEKKESSPSGSSSEDDSASSNDDDQRSPSATSSFIFPP---------- 72

  Fly    58 ATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVL 122
               :||::.:.|.:|.|.|           .|....:..||             ||....|..:|
 Worm    73 ---ASSSSSSESATSPTQI-----------MAQLMANGGAV-------------DPGLQAYFFLL 110

  Fly   123 QLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYM 187
            |.|.|....|.......|:.|           .:.|.:                .|..|.|...:
 Worm   111 QSQLNSQSMMNRVTQENVSRA-----------LTSFNL----------------LNNLPGALPSL 148

  Fly   188 SNFG--------------VKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQV 238
            |..|              :::|..:..||..|...||.:|..:|||:..:|..||.:|.:::.||
 Worm   149 SPMGRLQHSMQLSPNSLNMQKKQSRPTFTGHQIYQLERKFEQTKYLAGADRAQLAQELNMSESQV 213

  Fly   239 KTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPVLNLG 287
            |.||||||.|||     |:.|:....:...|.|..|..|.|  |.|:.|
 Worm   214 KVWFQNRRTKWR-----KKEAADNALVKRGASGDKSPCSLS--PFLSAG 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/50 (48%)
cog-1	NP_001022264.1	Homeodomain	170..226	CDD:459649	26/60 (43%)