Protein Alignment HHEX and Hoxd4

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_034599.2
• Gene: Hoxd4 / 15436
• MGIID: 96208
• Length: 250
• Species: Mus musculus
• Alignment Length: 257
• Identity: 60/257 - (23%)
• Similarity: 84/257 - (32%)
• Gaps: 105/257 - (40%)

  Fly    31 RGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDS 95
            ||..|.|....:....|            |....||.|:|        |....|.:|
Mouse    76 RGHGQEPSGPGSHYGAP------------GERCPAPPPAP--------LPGARACSQ-------- 112

  Fly    96 SAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTM 160
                 ||    .|..|.|.:..        |.|::..|..:...|.:.
Mouse   113 -----PT----GPKQPPPGTAL--------KQPAVVYPWMKKVHVNSV----------------- 143

  Fly   161 DCEGFPNPASAAAALYCNAYPAASFYMSNF-GVKRKGGQIRFTSQQTKNLEARFASSKYLSPEER 224
                  ||                    |: |.:.|..:..:|.||...||..|..::||:...|
Mouse   144 ------NP--------------------NYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRR 182

  Fly   225 RHLALQLKLTDRQVKTWFQNRRAKWRR----ANLSKRSASAQGPIAGAAVGSPSSASSSSVP 282
            ..:|..|.|::||:|.||||||.||::    .|...||:|:            ||.|||:.|
Mouse   183 IEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSS------------SSCSSSAAP 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/50 (46%)
Hoxd4	NP_034599.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..126		18/94 (19%)
		Antp-type hexapeptide	131..136		1/4 (25%)
		Homeodomain	153..209	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..250		10/35 (29%)