Protein Alignment HHEX and Hoxd12

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_032300.2
• Gene: Hoxd12 / 15432
• MGIID: 96204
• Length: 268
• Species: Mus musculus
• Alignment Length: 266
• Identity: 60/266 - (22%)
• Similarity: 101/266 - (37%)
• Gaps: 58/266 - (21%)

  Fly    18 LEQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPS-PSSATNIYDLSR 81
            |:...|.:.|..|...||        :|....::.|:::|...::.|:.||: |::|:.....|:
Mouse    18 LQSPDSFYFSNLRANGSQ--------LAALPPISYPRSALPWATTPASCTPAQPATASAFGGFSQ 74

  Fly    82 EAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAV 146
            ........:......|...|         .|....:........:..|...|.|...:....:|:
Mouse    75 PYLTGSGPIGLQSPGAKDGP---------EDQVKFYTPDAPTASEERSRTRPPFAPESSLVHSAL 130

  Fly   147 QPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMS-------NFGVKRKG-------- 196
            :.|.|         |..|....|..:|.|...|..|:||...       |..|:..|
Mouse   131 KGTKY---------DYAGVGRTAPGSATLLQGAPCASSFKEDTKGPLNLNMAVQVAGVASCLRSS 186

  Fly   197 -----------GQIR-----FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNR 245
                       |:.|     :|.||...||..|..:::::.::|:.|:.:|.|:|:|||.|||||
Mouse   187 LPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNR 251

  Fly   246 RAKWRR 251
            |.|.:|
Mouse   252 RMKKKR 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	22/55 (40%)
Hoxd12	NP_032300.2	PHA03247	<37..123	CDD:223021	15/94 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..124		3/21 (14%)
		Homeodomain	201..257	CDD:459649	22/55 (40%)