Protein Alignment HHEX and Hoxa4

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_032291.1
• Gene: Hoxa4 / 15401
• MGIID: 96176
• Length: 285
• Species: Mus musculus
• Alignment Length: 245
• Identity: 68/245 - (27%)
• Similarity: 92/245 - (37%)
• Gaps: 45/245 - (18%)

  Fly    47 PHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNP--- 108
            |||...|.|..|..:.      .||....:|  ...|||..||.:.      .:|.....:|
Mouse    56 PHAARQPPAYYAPRAR------EPSYPGGLY--PAPAAACPYACRG------ASPARPEQSPAPG 106

  Fly   109 IYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVA--AAAAVQPTAYCDQYSPFTMDCEGFPNPASA 171
            .:|.||.       |....|....|.....|||  .:|...|....||         |...|...
Mouse   107 AHPSPAP-------QPPAPPRHCAPGPTTPAVATGGSAPACPLLLADQ---------GPAGPKGK 155

  Fly   172 AAALY--CNAYPAASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLT 234
            ...:|  ......::...|..|.:.|..:..:|.||...||..|..::||:...|..:|..|.|:
Mouse   156 EPVVYPWMKKIHVSAVNSSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLS 220

  Fly   235 DRQVKTWFQNRRAKWRR----ANLSKRSASAQGPIAGAAVGSPSSASSSS 280
            :||||.||||||.||::    .|...||::.    |.|..|.|..|.:.|
Mouse   221 ERQVKIWFQNRRMKWKKDHKLPNTKMRSSNT----ASAPAGPPGKAQTHS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/50 (48%)
Hoxa4	NP_032291.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..70		6/13 (46%)
		PHA03247	<43..161	CDD:223021	31/134 (23%)
		Antp-type hexapeptide	159..164		1/4 (25%)
		Homeodomain	181..237	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..285		9/33 (27%)