Protein Alignment HHEX and Hlx

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_032276.1
• Gene: Hlx / 15284
• MGIID: 96109
• Length: 476
• Species: Mus musculus
• Alignment Length: 323
• Identity: 87/323 - (26%)
• Similarity: 130/323 - (40%)
• Gaps: 49/323 - (15%)

  Fly    10 AAFSIENILEQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSAT 74
            |||  ...|.|:|.:.:.|.::.....|.||:....|.....:|..|   ||:     |:|||..
Mouse   116 AAF--HQHLPQQSPTQQQQPQQQPPPPPRAVSLQPPTSGTRVVPHHS---GSA-----PAPSSKD 170

  Fly    75 NIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFM----PHF 135
            ..:.:.| ..:|::..|..:.:.:...|||...   ..||.:   .:..||.:...|.    |..
Mouse   171 LKFGIDR-ILSAEFDPKVKEGNTLRDLTSLLTG---GRPAGV---HLAGLQPSAGQFFASLDPIS 228

  Fly   136 QAAAVAAAAAVQP-TAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVKRKGGQI 199
            :|:|:.:..:..| .:...|:.      :.||.|   .|.|..:..|      ..:..||...:.
Mouse   229 EASAILSPLSSNPRNSVQHQFQ------DTFPGP---YAVLTKDTMP------QTYKRKRSWSRA 278

  Fly   200 RFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWR-----RANLSKRSA 259
            .|::.|.|.||.||...||::..:|:.||..|.|||.|||.||||||.|||     :|...|...
Mouse   279 VFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKE 343

  Fly   260 SAQGPIAGA-AVGSPSSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDEDDDEDEGEADET 321
            :.:.|..|. |.|.....|.|.      ..|....:.||.|.......|.|..:..|....:|
Mouse   344 AGEKPSGGVPAEGEREERSPSR------SEGEAESESSDSESLDMAPSDTERTEGTERSLHQT 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	28/55 (51%)
Hlx	NP_032276.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..169		15/56 (27%)
		Homeodomain	270..330	CDD:459649	29/59 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..401		18/79 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..476