Protein Alignment HHEX and Dlx1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_034183.1
• Gene: Dlx1 / 13390
• MGIID: 94901
• Length: 255
• Species: Mus musculus
• Alignment Length: 290
• Identity: 71/290 - (24%)
• Similarity: 111/290 - (38%)
• Gaps: 76/290 - (26%)

  Fly    47 PHALAMPKASLAT----GSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFN 107
            |.:|..|.:..|.    |..:...:|||.|            ...|:|..:.|:....|     :
Mouse     7 PESLNSPVSGKAVFMEFGPPNQQMSPSPMS------------HGHYSMHCLHSAGHSQP-----D 54

  Fly   108 PIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAA 172
            ..|...:|.          :..|..|:..:.:..|:            ||:....:.:|..||.|
Mouse    55 GAYSSASSF----------SRPLGYPYVNSVSSHAS------------SPYISSVQSYPGSASLA 97

  Fly   173 AALYCNAYPAASFYMSNFGVKRKGGQIRF--------------TSQQTKNLEARFASSKYLSPEE 223
            .:...:  |.|.   |......:||::||              :|.|.:.|..||..::||:..|
Mouse    98 QSRLED--PGAD---SEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPE 157

  Fly   224 RRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPV----- 283
            |..||..|.||..|||.||||:|:|:::  |.|:..:|   :.|:|:.:..:.|:.|.||
Mouse   158 RAELAASLGLTQTQVKIWFQNKRSKFKK--LMKQGGAA---LEGSALANGRALSAGSPPVPPGWN 217

  Fly   284 ----LNLGSGSRCGQQSDEEDRMYLSEDDE 309
                ...||||..|.........|.|...|
Mouse   218 PNSSSGKGSGSSAGSYVPSYTSWYPSAHQE 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	25/64 (39%)
Dlx1	NP_034183.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		9/42 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		6/27 (22%)
		Homeodomain	129..185	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..233		9/28 (32%)