Protein Alignment HHEX and Gbx2

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_446160.1
• Gene: Gbx2 / 114500
• RGDID: 621866
• Length: 348
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 90/355 - (25%)
• Similarity: 119/355 - (33%)
• Gaps: 124/355 - (34%)

  Fly     8 SKAAFSIENIL---EQKSSSHRSQSRRG----SSQSPVAVTAGIATPHAL-------AMPKA--- 55
            |..||||::::   .|.|..|...:  |    ....||.:......|.||       |:|.|
  Rat    18 SSTAFSIDSLIGSPPQPSPGHFVYT--GYPMFMPYRPVVLPPPPPPPPALPQAALQPALPPAHPH 80

  Fly    56 ----SLATG------------SSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSL 104
                ||.||            |:..|..|...||:..:   :|||||:          ..||..|
  Rat    81 HQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQH---QEAAAAR----------KFAPQPL 132

  Fly   105 RFNPIYPDPASLFYQQVLQ---------LQKNPSLFMPHFQAAAVAAAAAV-------------- 146
                  |...:....:.||         |.|..||..  |.||....|:.|
  Rat   133 ------PGGGNFDKSEALQADTEDGKAFLAKEGSLLA--FSAAEAVQASLVGAVRGQGKDESKVE 189

  Fly   147 -QPTAYCDQYS-----PFTMD-----------------CEGFPNPASAAAALYCNAYPAASFYMS 188
             .|....:.:|     .::.|                 .|..|....||.:.....
  Rat   190 DDPKGKEESFSLESDVDYSSDDNLPGQTAHKEEDPGHALEETPQSGGAAGSTTSTG--------- 245

  Fly   189 NFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRAN 253
                |.:..:..|||:|...||..|...||||..||..:|..|||::.|||.|||||||||:|..
  Rat   246 ----KNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVK 306

  Fly   254 LSKRSASAQGPIAGAAVGSPSSASSSSVPV 283
            ...         |.:..|.||......||:
  Rat   307 AGN---------ANSKTGEPSRNPKIVVPI 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	29/50 (58%)
Gbx2	NP_446160.1	Homeodomain	248..304	CDD:459649	29/55 (53%)