Protein Alignment HHEX and en2

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: XP_002932525.1
• Gene: en2 / 100498251
• XenbaseID: XB-GENE-853108
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 284
• Identity: 63/284 - (22%)
• Similarity: 108/284 - (38%)
• Gaps: 77/284 - (27%)

  Fly    12 FSIENIL------EQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSP 70
            |.|:|||      .::..||:.:...|.....:   :|..:.|..|  .|:...|.|.|......
 Frog    42 FFIDNILRPEFGRRKEGISHQDELFSGRDSGAL---SGAESAHHRA--NATEGAGGSKAITLTGD 101

  Fly    71 SSATNIYDLSREAAA------AQYAMKS-MDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNP 128
            ..:    |::.|.:.      ..:::.| .|||...:.||                      :.|
 Frog   102 KKS----DIAMEESLKSRGHNGDHSLSSDSDSSQASSKTS----------------------QQP 140

  Fly   129 SLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVK 193
            .|: |.:              .||.:||         ..|:|...:.........:....:
 Frog   141 MLW-PAW--------------VYCTRYS---------DRPSSGPRSRKPKKKTTTTVTKED---- 177

  Fly   194 RKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRS 258
             |..:..||:.|.:.|:|.|.:::||:.:.|:.||.:|.|.:.|:|.||||:|||.::|..:|.|
 Frog   178 -KRPRTAFTADQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNS 241

  Fly   259 AS----AQGPIAGAAVGSPSSASS 278
            .:    |||....:.....|.:.|
 Frog   242 LALHLMAQGLYNHSTTSKDSKSDS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	22/50 (44%)
en2	XP_002932525.1	Homeodomain	178..234	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	235..265	CDD:431338	7/29 (24%)