Protein Alignment HHEX and hoxd8

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001135589.1
• Gene: hoxd8 / 100216142
• XenbaseID: XB-GENE-920113
• Length: 231
• Species: Xenopus tropicalis
• Alignment Length: 238
• Identity: 58/238 - (24%)
• Similarity: 91/238 - (38%)
• Gaps: 86/238 - (36%)

  Fly    32 GSSQSPVAVTAGIATPHALAMPKASLATGSSSAAP---------TPSPSSATNIYDLSREAAAAQ 87
            ||.::|:                  :.:||.|.||         .|||....
 Frog    31 GSGRAPL------------------VYSGSGSGAPQDYYHHPGTLPSPGYQP------------- 64

  Fly    88 YAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYC 152
                        ||..:   ..:.|||.|:.....|.|   .:|..|.:|         :|..|
 Frog    65 ------------APCGI---TCHGDPAKLYGYDHFQRQ---HIFTTHQEA---------EPVQY- 101

  Fly   153 DQYSPFTMDCEGFPNPASAAAA----LYCNAYPAASFY---MSNFGVKRKGGQIRFTSQQTKNLE 210
                   .||:   :|:::..|    |:.|: ||:..:   .:.....|:.|:..::..||..||
 Frog   102 -------PDCK---SPSASIGADPEHLHQNS-PASHMFPWMRAQVAPGRRRGRQTYSRFQTLELE 155

  Fly   211 ARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRAN 253
            ..|..:.||:.:.|..::..|.||:||||.||||||.||::.|
 Frog   156 KEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/50 (46%)
hoxd8	NP_001135589.1	Homeodomain	140..196	CDD:459649	24/55 (44%)