Protein Alignment dmrt93B and C18orf63

DIOPT Version :10

• Sequence 1: NP_524428.1
• Gene: dmrt93B / 42494
• FlyBaseID: FBgn0038851
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_001167594.1
• Gene: C18orf63 / 644041
• HGNCID: 40037
• Length: 685
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 56/281 - (19%)
• Similarity: 97/281 - (34%)
• Gaps: 68/281 - (24%)

  Fly    15 KRPRLVANPKATKIVEPTPAKVTNRVPKCAR----CR---NH-----------GIISEL------ 55
            |.|.|...    |::..:..:.|:|.|.||:    |.   :|           ||.|.|
Human   331 KPPNLTTK----KMLRASLTQATSRKPACAQSLLPCSVAVDHKVELSVSQPTSGIFSALHLQPES 391

  Fly    56 -RGHKKLCTYKNCKCAKCVLIFERQRIMAAQVALKRQQAVEDAIAMRLVANKTGRSIDALPPGNI 119
             :|.||..:.:..:....||:..|.........|..|    ..|..:.|.....|.:......::
Human   392 VQGRKKSLSIRAPQVHSEVLMPNRGNTQVQHTNLSSQ----SNITPKFVPVFKNRLLQMNKNTSV 452

  Fly   120 FGLTVTQPSSPRAKREDDQVEKTISEVEQ--QH--------LKQREEEYSESPA---VAQDLSAP 171
            .|       ||:.|:.|....|..|....  ||        :|.|.....:..|   :.|:.|.|
Human   453 LG-------SPKRKQHDVTQSKLFSLKTSMIQHDKLNLGPAIKNRYSSNIQMQAANNLNQENSRP 510

  Fly   172 RRDNVSQTAIDMLAQLFP-QRKRSVLEL------------VLKRCDLDLIRAIENVSPTGKSSPV 223
            .::..::::.:|..  || .|.:|.:.|            |:...:|.::::..:....||.:..
Human   511 LQEKNTESSENMTK--FPSSRGKSTVSLNKNKQLSNSAVFVVSNNNLGVVKSAVDFQMKGKENLT 573

  Fly   224 DVTSNQLPSQEPGMLTTMPQP 244
            .....|:..:..|.|....||
Human   574 GKGITQILGKSHGSLKLKRQP 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmrt93B	NP_524428.1	DM	39..85	CDD:459924	16/70 (23%)
		CUE_DMA	176..214	CDD:270553	8/50 (16%)
C18orf63	NP_001167594.1	DUF4708	7..280	CDD:464889
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	502..538		9/37 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	635..685