Protein Alignment dmrt93B and DMRT3

DIOPT Version :9

• Sequence 1: NP_524428.1
• Gene: dmrt93B / 42494
• FlyBaseID: FBgn0038851
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_067063.1
• Gene: DMRT3 / 58524
• HGNCID: 13909
• Length: 472
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 112/452 - (24%)
• Similarity: 161/452 - (35%)
• Gaps: 186/452 - (41%)

  Fly    29 VEPTPAKVTNRVPKCARCRNHGIISELRGHKKLCTYKNCKCAKCVLIFERQRIMAAQVALKRQQA 93
            |...|.....|.||||||||||::|.|:|||:.|.:|:|.|.||:||.||||:|||||||:||||
Human    15 VSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQA 79

  Fly    94 VEDAIAMRLVANKTGRSIDAL----PPGNIFGL----TVTQPSSPRAKR---------------- 134
            .|...:  |:.:    |:.||    |||:....    ..:|||.|:..|
Human    80 NESLES--LIPD----SLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAE 138

  Fly   135 -----------EDDQVEKTISEVEQ----QHLKQREEEYSESPAVAQD----------------- 167
                       :.|..|:.:.:.:.    :....::.:...||.||:.
Human   139 PQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEG 203

  Fly   168 -----------------------------------LSAPRRDNVSQTAIDMLAQLFPQRKRSVLE 197
                                               :|.|.....::..:::|.::||.:|.:|||
Human   204 GYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLE 268

  Fly   198 LVLKRCDLDLIRAIE-----NVSPTG------------------------KSSPVDV-------- 225
            |:||.|..||:.|:|     ..|.||                        .|.|:..
Human   269 LILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSA 333

  Fly   226 ------------TSNQLPSQEPGMLTTMPQPAPPR-------------SSAFRP---------VI 256
                        :||.:||...|.|.. |.|.|||             ||.|.|         .:
Human   334 FRVPDTLRFSADSSNVVPSPLAGPLQP-PFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTL 397

  Fly   257 TDQYQSKSVVELKPPVFGGSASAAAAAAICAYPKWFVPLSFPVTMGHLSNLAPRCTLPNCAC 318
            ..|||.:|  :...|....|.|              |..|.||.....:. .||.::|:..|
Human   398 QQQYQLRS--QYVSPFPSNSTS--------------VFRSSPVLPARATE-DPRISIPDDGC 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmrt93B	NP_524428.1	DM	39..85	CDD:279137	30/45 (67%)
		CUE_DMA	176..214	CDD:270553	15/42 (36%)
DMRT3	NP_067063.1	DM	25..71	CDD:279137	30/45 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..128		11/42 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..191		5/35 (14%)
		CUE_DMA_DMRTA3	247..289	CDD:270602	15/41 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	430..472		4/14 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	140	1.000	Inparanoid score	I4503
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383821at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12322
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3693
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.960