Protein Alignment dmrt93B and Dmrta2

DIOPT Version :10

• Sequence 1: NP_524428.1
• Gene: dmrt93B / 42494
• FlyBaseID: FBgn0038851
• Length: 325
• Species: Drosophila melanogaster
• Sequence 2: NP_001101421.2
• Gene: Dmrta2 / 313471
• RGDID: 1308173
• Length: 536
• Species: Rattus norvegicus
• Alignment Length: 485
• Identity: 122/485 - (25%)
• Similarity: 176/485 - (36%)
• Gaps: 194/485 - (40%)

  Fly     2 ASSSGEPADEVAN---------KRPRLVAN------PKATKIVEPTPAKVTNRVPKCARCRNHGI 51
            |:::|.|...||:         ..|..||.      |...:..|..|     |.||||||||||:
  Rat    18 ATATGPPVASVASVAAAAAAAASLPVSVAGGLLRAPPLLLRAAEKYP-----RTPKCARCRNHGV 77

  Fly    52 ISELRGHKKLCTYKNCKCAKCVLIFERQRIMAAQVALKRQQAVEDAIAMR---LVANKTGRSIDA 113
            :|.|:|||:.|.:|:|.||||.||.||||:|||||||:||||.|:..|..   |.....|.::.|
  Rat    78 VSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAA 142

  Fly   114 ----LPPG---NIFG------------------------------------------LTVTQPSS 129
                :||.   .:||                                          |...:|.|
  Rat   143 ANGIIPPRPAYEVFGSVCATDGGGPGAGAPAGSAGGAGGAGGAEAKLQKFDLFPKTLLQAGRPDS 207

  Fly   130 P--------------------------------------------RAKR---------------- 134
            |                                            ||.:
  Rat   208 PQPPPGKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGASGGG 272

  Fly   135 EDDQV-------EKTISEVEQQHLKQREEEYSESPAVAQDLSAPRRDNVSQTAIDMLAQLFPQRK 192
            |:|..       .::.||.:::     |.|.:.:|.:... ..||:    :|.:|:|.::||..:
  Rat   273 EEDSPGSSSPLGSESGSEADKE-----EAEAAPTPGLGGG-PGPRQ----RTPLDILTRVFPGHR 327

  Fly   193 RSVLELVLKRCDLDLIRAIENV---------SPTGKSSPVD--------VTSNQLPSQE------ 234
            |.||||||:.|..|:::|||.|         :..|.::|::        ...:..|.:.
  Rat   328 RGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPLEKAAVSAAAAVEDAWPGRVEAAAAG 392

  Fly   235 ----PGMLTTMPQPAPPR-----SSAFRPVITDQYQSKSVVE-LKPPV--FGGSASAAAAAAICA 287
                |..|.|.| .|||.     :.|..|.......|:|... |:|..  ||..|.|....|
  Rat   393 GAGLPAPLQTGP-AAPPHHRPLLAGAMTPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGA--- 453

  Fly   288 YPKWFVP--LSFPVTMGH---LSNLAPRCT 312
             |....|  |::.....|   |:.:||..|
  Rat   454 -PLGLSPLRLAYSAAAAHSRGLAFMAPYST 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmrt93B	NP_524428.1	DM	39..85	CDD:459924	31/45 (69%)
		CUE_DMA	176..214	CDD:270553	17/37 (46%)
Dmrta2	NP_001101421.2	DM	65..111	CDD:459924	31/45 (69%)
		CUE_DMA_DMRTA2	311..352	CDD:270601	19/44 (43%)
		DMRT5_DMB	428..507	CDD:466773	17/59 (29%)