DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmrt93B and Dmrta1

DIOPT Version :9

Sequence 1:	NP_524428.1	Gene:	dmrt93B / 42494	FlyBaseID:	FBgn0038851	Length:	325	Species:	Drosophila melanogaster
Sequence 2:	NP_783578.1	Gene:	Dmrta1 / 242523	MGIID:	2653627	Length:	490	Species:	Mus musculus

Alignment Length:	269	Identity:	74/269 - (27%)
Similarity:	112/269 - (41%)	Gaps:	93/269 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RVPKCARCRNHGIISELRGHKKLCTYKNCKCAKCVLIFERQRIMAAQVALKRQQAVEDAIAMRL- 102
            |.||||||||||::|.|:|||:.|.:::|.||||.||.||||:|||||||:||||.|::.|..|
Mouse    82 RTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLH 146

  Fly   103 -------------VANKTGRSIDALPPGNIFGLTV------TQPSS------------------- 129
                         .:..:||:.......|...:.|      ..|.|
Mouse   147 RLLYQGSSGSGAQASGGSGRTESPQVLNNPMAVAVLGAGASRHPGSRSVPTFEVFQQDYADRKQE 211

  Fly   130 PRAK-------REDDQVEKTISE----------VEQQHLKQREEEYSESPAV------------- 164
            |:.:       |:::.|..|...          ||:|.......|:.:...:
Mouse   212 PKQRNCESCQSRQEEPVSNTHHHSLGSSKGNVTVEKQGFMSSIPEHPDKSTIILSPCPTDQSGGE 276

  Fly   165 -------AQDLSAPR-----RDNVSQTA------------IDMLAQLFPQRKRSVLELVLKRCDL 205
                   :.||.:..     ||.::..|            :.:|.::||..|.|.||.:|:.|..
Mouse   277 DSPRSFSSSDLESGNESEWARDYIATRASLSTVTSRPRDPLGILTRIFPGYKHSRLEGILQFCKG 341

  Fly   206 DLIRAIENV 214
            |:::|||.:
Mouse   342 DVVQAIEQI 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmrt93B	NP_524428.1	DM	39..85	CDD:279137	30/45 (67%)
dmrt93B	NP_524428.1	CUE_DMA	176..214	CDD:270553	14/49 (29%)
Dmrta1	NP_783578.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		DM	82..128	CDD:279137	30/45 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	152..171		2/18 (11%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..289		10/81 (12%)
		DMA	315..350	CDD:281472	13/34 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12322
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3693
SonicParanoid	1	1.000	-	-		X984
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.900