DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and ANN5

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_564920.1	Gene:	ANN5 / 843137	AraportID:	AT1G68090	Length:	316	Species:	Arabidopsis thaliana

Alignment Length:	311	Identity:	107/311 - (34%)
Similarity:	166/311 - (53%)	Gaps:	4/311 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKS 77
            |...|:    |..||..|.||.||.|.|...||.|||.|...||..|.:.::|.:..||...|.|
plant     7 PMTVPS----PRVDADQLFKAFKGRGCDTSVIINILAHRNATQRALIEQEYETKFSDDLRKRLHS 67

  Fly    78 ELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKS 142
            ||.|..:..:|..|....:..|..|..::.|..||.:||.||:||.|...::.|.|.|..:||..
plant    68 ELHGHLKKAVLLWMPEAVERDASILKRSLRGAVTDHKAIAEIICTRSGSQLRQIKQVYSNTFGVK 132

  Fly   143 LESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITR 207
            ||.|::.:.||:.||:.::.:...|.|...:|.|:...||:.|..|...:..:|:.|...|...|
plant   133 LEEDIESEASGNHKRVLLAYLNTTRYEGPEIDNASVENDARTLKSAVARKHKSDDQTLIQIFTDR 197

  Fly   208 SYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKD 272
            |...|..:...|.::.|.::.|||:.|..|:.|...|.|::|.::...||::.|..||.|:||.|
plant   198 SRTHLVAVRSTYRSMYGKELGKAIRDETRGNFEHVLLTILQCAENSCFYFAKALRKSMKGLGTDD 262

  Fly   273 KTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            ..||||:|:|:|:|:..|...::.:|.|:|.:.:..||:..|:..||:::|
plant   263 TALIRIVVTRAEVDMQFIITEYRKRYKKTLYNAVHSDTTSHYRTFLLSLLG 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	27/63 (43%)
		Annexin	97..162	CDD:395139	24/64 (38%)
		Annexin	188..246	CDD:395139	16/57 (28%)
		Annexin	256..321	CDD:395139	26/64 (41%)
ANN5	NP_564920.1	Annexin	16..80	CDD:278615	27/63 (43%)
		Annexin	87..151	CDD:278615	24/63 (38%)
		Annexin	171..236	CDD:278615	19/64 (30%)
		Annexin	246..311	CDD:278615	26/64 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	65	1.000	Domainoid score	I3619
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I1373
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D856254at2759
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm965
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	1	1.100	-	-	O	PTHR10502
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840