DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa13

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_571849.2	Gene:	anxa13 / 81880	ZFINID:	ZDB-GENE-010406-1	Length:	316	Species:	Danio rerio

Alignment Length:	312	Identity:	154/312 - (49%)
Similarity:	207/312 - (66%)	Gaps:	0/312 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 CTPTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDL 75
            |.||:.|.:.||.:.|...:|||.|||||||||||:|||.|...||:||.:|:...|..:|:..|
Zfish     4 CQPTIVPYEDFDVIADIKAIRKACKGFGTDEKAIIDILAYRSAAQRMEIKQAYFEKYDDELVDVL 68

  Fly    76 KSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFG 140
            ||||.|.||:.|||::.|...|..:||..|:.|.||||:.::|||||.:|..|....:.|.|...
Zfish    69 KSELSGNFENAILAMLDPPHVFAVKELRKAMKGAGTDEDVLVEILCTATNDEIAFYKETYTQVHD 133

  Fly   141 KSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILI 205
            :.||||::|||||..:||...|:||||||:..||||.|..||.:|.:||||..|||||||:.||.
Zfish   134 RDLESDIEGDTSGDVRRLLTLLLQGNRDESYEVDEALAEQDAVSLFEAGEGSLGTDESTFSYILA 198

  Fly   206 TRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGT 270
            ||:|.||:..|..||.:||.||..||.:|.||:::..:..:|:|.|:...:|:.||:.:|.|.||
Zfish   199 TRNYLQLQVTFKAYEAISGTDILDAIDKETSGTLKDCYTTLVRCAKNPQLFFARRLNAAMKGAGT 263

  Fly   271 KDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIV 322
            .:.|||||||.|||:||..||:.:..||..:|:..|..:..||:||.||||:
Zfish   264 DEDTLIRIIVCRSEVDLETIKDMYLEKYDVTLKDAISSECGGDFKRLLLAIL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	36/63 (57%)
		Annexin	97..162	CDD:395139	29/64 (45%)
		Annexin	188..246	CDD:395139	30/57 (53%)
		Annexin	256..321	CDD:395139	31/64 (48%)
anxa13	NP_571849.2	Annexin	19..83	CDD:278615	36/63 (57%)
		Annexin	90..155	CDD:278615	29/64 (45%)
		Annexin	173..239	CDD:278615	33/65 (51%)
		Annexin	249..314	CDD:278615	31/64 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.660