DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa6

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_002937305.2	Gene:	anxa6 / 779574	XenbaseID:	XB-GENE-989741	Length:	671	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	158/308 - (51%)
Similarity:	220/308 - (71%)	Gaps:	2/308 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELG 80
            ||  .||..:||.||.|||||||:|::||::::|.|...||::|.:|:|:.||||||.|||.||.
Frog    13 YP--DFDANQDAEILYKAMKGFGSDKEAILDLIASRSNHQRIQITQAYKSLYGKDLIDDLKYELT 75

  Fly    81 GKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLES 145
            ||||.:|:.||.|.|.|.|:|:.||::|.||||:.:||||.:.:|..:..:|..|:.::.:.||:
Frog    76 GKFERLIVGLMRPPPYFDAKEIKDALAGAGTDEKCLIEILASRNNQEVHALAAAYKDAYDRDLET 140

  Fly   146 DLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQ 210
            |:..|||||||::.:.|:||.|:|:..|.|.....|||.|.:|||.:|||||:.|..||.:||.|
Frog   141 DVIKDTSGHFKKMLIVLLQGTREEDDVVSEDLVEQDAQDLFEAGEQKWGTDEAQFIFILGSRSKQ 205

  Fly   211 QLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTL 275
            .|..:|.:|:.:||..||::||.|.||..:...||:|||.:|..:||:.||:.||.||||.|.||
Frog   206 HLHLVFDKYQEISGKTIEESIKAELSGDFQDLMLAVVKCIRSTREYFATRLYKSMKGMGTADNTL 270

  Fly   276 IRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            |||:|||||||:.:|:|:|:.||.|||.|.||.||||:||:.||.:.|
Frog   271 IRIMVSRSEIDMLNIRESFRTKYQKSLFSMIKNDTSGEYKKTLLKLCG 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	37/63 (59%)
		Annexin	97..162	CDD:395139	27/64 (42%)
		Annexin	188..246	CDD:395139	27/57 (47%)
		Annexin	256..321	CDD:395139	42/64 (66%)
anxa6	XP_002937305.2	Annexin	20..85	CDD:365936	37/64 (58%)
		Annexin	92..157	CDD:365936	27/64 (42%)
		Annexin	175..241	CDD:365936	31/65 (48%)
		Annexin	251..316	CDD:365936	42/64 (66%)
		Annexin	366..430	CDD:365936
		Annexin	437..502	CDD:365936
		Annexin	525..591	CDD:365936
		Annexin	601..666	CDD:365936
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9515
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920