DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and Anxa9

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001078852.1	Gene:	Anxa9 / 71790	MGIID:	1923711	Length:	345	Species:	Mus musculus

Alignment Length:	307	Identity:	99/307 - (32%)
Similarity:	165/307 - (53%)	Gaps:	14/307 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 FDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELGGKFED 85
            |...:|...|.||:.|.|.|...|:::|..|...||..|:.||:....:||:..|::.|.|..|.
Mouse    41 FSVDKDVQRLLKAIAGQGVDYDTIVDVLTNRSREQRQLISRAFQERTKQDLLKSLQAALSGNLEK 105

  Fly    86 VILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGD 150
            :::||:.|..||.||||..|:...|:.|:..:|||.|.:..|::.....|:..|....|.|::.:
Mouse   106 IVVALLQPAAQFDAQELRTALKTSGSAEDVALEILATRAAPGLQACLAVYKHDFQVEAEEDIRTE 170

  Fly   151 TSGHFKRLCVSLVQGNRDENQG-VDEAAAIADAQALHDAGE----GQWGTDESTFNSILIT-RSY 209
            |:|..:.|.::|.:|:|:...| :|......|.:||..|||    |||        .:|:| ||.
Mouse   171 TNGILQDLLLALSKGDRESYSGIIDYNLEEQDVRALQQAGESSTAGQW--------VLLLTQRSP 227

  Fly   210 QQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKT 274
            :.|.::|.:|...:|.::|.||:..|.|..:...:::....::...||:.:||.::.......:.
Mouse   228 EHLIRVFDQYRRCTGQELEDAIRNCFHGDAQLALISLASMLRNTALYFANKLHQALQETEPNFQV 292

  Fly   275 LIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAI 321
            |.|:::||||.||..|:..|:.|:||||.|.::....||.:.||||:
Mouse   293 LTRVLISRSESDLLSIRAEFKKKFGKSLYSSLQDVVRGDCRSALLAL 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	21/63 (33%)
		Annexin	97..162	CDD:395139	20/64 (31%)
		Annexin	188..246	CDD:395139	19/62 (31%)
		Annexin	256..321	CDD:395139	25/64 (39%)
Anxa9	NP_001078852.1	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	41..112		24/70 (34%)
		Annexin	46..110	CDD:395139	21/63 (33%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	113..184		23/70 (33%)
		Annexin	117..182	CDD:395139	20/64 (31%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	197..266		22/76 (29%)
		Annexin	<222..264	CDD:413385	12/41 (29%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	270..341		26/70 (37%)
		Annexin	274..339	CDD:395139	25/64 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831980
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D856254at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.760