DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa5a

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001107054.1	Gene:	anxa5a / 557578	ZFINID:	ZDB-GENE-080220-29	Length:	316	Species:	Danio rerio

Alignment Length:	310	Identity:	155/310 - (50%)
Similarity:	214/310 - (69%)	Gaps:	2/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSE 78
            :|.|...|:...||.:|||||||.||||..|:.:||.|...||.||..|:|.::||||:.||:||
Zfish     6 SVKPFVHFNAKHDAEVLRKAMKGIGTDEDTILMLLAARSNDQRQEIKAAYKKAFGKDLVKDLRSE 70

  Fly    79 LGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSL 143
            ||||.||:|:|||.|...:.|.|||.||.|:||:::.:||||.:.:...||.|.:.|::..|..|
Zfish    71 LGGKLEDLIVALMAPPTIYDANELHKAIKGVGTEDQVLIEILASRTCEEIKEIVKAYKKEHGGKL 135

  Fly   144 ESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRS 208
            |.|:.||||||::::.|.|||..|:|  ||||:....||:.|..|||.::||||..|.:||..||
Zfish   136 EKDIMGDTSGHYQKMLVILVQAGREE--GVDESRVEKDAKELFAAGEEKFGTDEDKFINILGNRS 198

  Fly   209 YQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDK 273
            .:.||::|..|:.::|.|||:::|.|.:|::|...||:|||.||...||:|.|.:||...||.|:
Zfish   199 AEHLRKVFEAYKKIAGCDIEESLKEECTGNLEALLLAVVKCAKSVPAYFAECLRESMRRAGTDDE 263

  Fly   274 TLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            |||||:|||||.|:.||:.|::.|||.||.|.|:.||.|||::|||.:.|
Zfish   264 TLIRIMVSRSERDMLDIRAAYKKKYGDSLYSTIQEDTDGDYQKALLYLCG 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	38/63 (60%)
		Annexin	97..162	CDD:395139	28/64 (44%)
		Annexin	188..246	CDD:395139	25/57 (44%)
		Annexin	256..321	CDD:395139	38/64 (59%)
anxa5a	NP_001107054.1	Annexin	17..82	CDD:278615	38/64 (59%)
		Annexin	89..154	CDD:278615	28/64 (44%)
		Annexin	171..236	CDD:278615	28/64 (44%)
		Annexin	246..311	CDD:278615	38/64 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm6419
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.660