DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa13l

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001019585.1	Gene:	anxa13l / 554118	ZFINID:	ZDB-GENE-050522-310	Length:	316	Species:	Danio rerio

Alignment Length:	310	Identity:	145/310 - (46%)
Similarity:	201/310 - (64%)	Gaps:	0/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKS 77
            ||:.|.:.||.|.|...:|||.||.||||:.||.|||.|...|||||.:|:...|..||...||:
Zfish     6 PTITPFEDFDVVADIKTIRKACKGMGTDEETIISILANRSAAQRLEIKQAYFEKYDDDLEEVLKN 70

  Fly    78 ELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKS 142
            ||.|.||:.::|::.|...|.|:||..|:.|.||||:.::|||||.:|..|....:.|.|...:.
Zfish    71 ELTGNFENAVIAMLDPPNVFMAKELRRAMKGAGTDEDVLVEILCTSTNQDILNCKEAYLQVHERD 135

  Fly   143 LESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITR 207
            ||:|::.||||..:.|.|||:|.:|||...||||.|..||.:|.:||||::|||||||..||..|
Zfish   136 LEADIEDDTSGEVRNLLVSLLQADRDEAYEVDEALAEQDATSLIEAGEGRFGTDESTFTYILTHR 200

  Fly   208 SYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKD 272
            :|.||:..|..||.|||.||..||..|.:|:::..::.:|:|.|:...||:.||:.:|.|.||.:
Zfish   201 NYLQLQATFKIYETLSGTDILDAIDSEATGTLKDCYVTLVRCAKNPQLYFARRLNAAMKGAGTDE 265

  Fly   273 KTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIV 322
            :|||||||.|||:||..||:.:..||..:|:..:..:..||:||.|:.|:
Zfish   266 ETLIRIIVGRSEVDLETIKDMYLEKYDVTLKDALSSECGGDFKRLLIEIL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	32/63 (51%)
		Annexin	97..162	CDD:395139	28/64 (44%)
		Annexin	188..246	CDD:395139	29/57 (51%)
		Annexin	256..321	CDD:395139	30/64 (47%)
anxa13l	NP_001019585.1	Annexin	19..83	CDD:278615	32/63 (51%)
		Annexin	92..155	CDD:278615	27/62 (44%)
		Annexin	173..239	CDD:278615	32/65 (49%)
		Annexin	249..312	CDD:278615	29/62 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574824
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.660