DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa1d

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001017605.1	Gene:	anxa1d / 550268	ZFINID:	ZDB-GENE-050417-72	Length:	340	Species:	Danio rerio

Alignment Length:	310	Identity:	124/310 - (40%)
Similarity:	186/310 - (60%)	Gaps:	0/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSE 78
            ||.....|:...||..|:||::..|.||.||||:||:|...||.:|..|::.|.||.|..:||..
Zfish    29 TVKADSNFNAQNDAEKLKKAIETKGVDEAAIIEVLAKRSNAQRQQIKAAYQQSAGKPLADELKKA 93

  Fly    79 LGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSL 143
            |....|||:|||:....::.|.|:..|:.||||.|..:.|||.|.:|..|..:...:::.:.::|
Zfish    94 LKSHLEDVVLALLMTPSEYDAFEMRRAMKGLGTKENVLSEILGTRTNKEITALKNSFKEVYRETL 158

  Fly   144 ESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRS 208
            |.|:|.|.||:.:.:.:||.:..|.|::.:|:..|.:||:||.:||:.:.||..|....||..||
Zfish   159 EEDIKHDVSGNLETVLLSLCKATRSEDRKIDDGLAKSDAKALFEAGKNRIGTVCSVLIDILTNRS 223

  Fly   209 YQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDK 273
            ..||.:||..|...|.:.:.|.::.|.||..|...:.:||...:|..||:|:|..:|.|.||.:.
Zfish   224 EAQLCKIFQYYGQFSKDGLAKDLQSELSGDFEDCMMTLVKVAWNKPAYFAEKLQHAMKGFGTNND 288

  Fly   274 TLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            ||||||||||||||..|.:.::..|||:|:..|:.:|.|||::.||.:.|
Zfish   289 TLIRIIVSRSEIDLLKIMQEYKRMYGKTLQEAIQSETKGDYEKILLVLCG 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	30/63 (48%)
		Annexin	97..162	CDD:395139	21/64 (33%)
		Annexin	188..246	CDD:395139	20/57 (35%)
		Annexin	256..321	CDD:395139	34/64 (53%)
anxa1d	NP_001017605.1	Annexin	41..105	CDD:278615	30/63 (48%)
		Annexin	112..177	CDD:278615	21/64 (33%)
		Annexin	196..261	CDD:278615	24/64 (38%)
		Annexin	271..336	CDD:278615	34/64 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574831
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.860