DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AnxB9 and anxa1c

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_861425.1	Gene:	anxa1c / 494158	ZFINID:	ZDB-GENE-030131-5274	Length:	341	Species:	Danio rerio

Alignment Length:	323	Identity:	129/323 - (39%)
Similarity:	190/323 - (58%)	Gaps:	8/323 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FKCTP--------TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKT 65
            ||..|        ||.....|:...|||.|:||::..|.||..|||:||::...||.:|..|::.
Zfish    17 FKAAPAFETGYFGTVKADTNFNAQNDAAKLKKAIETKGVDEATIIEVLAKKSNAQRQQIKAAYQQ 81

  Fly    66 SYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKT 130
            |.||.|...||..|....|||:|||:....::.|.|:.:|:.||||.|..:.|||.|.||..|..
Zfish    82 SAGKPLADALKKALSSHLEDVVLALLMTPSEYDAFEMKNALKGLGTSENVLSEILGTRSNKEITA 146

  Fly   131 IAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGT 195
            :...:::.:|:.||.|:..|..|:.:...::|.:..|.|::.:|:|.|.:||:||.:|||.:.||
Zfish   147 LKNSFKEVYGEMLEEDINSDVKGNLETALLALCKATRSEDRNIDDAQAKSDAKALFEAGENRIGT 211

  Fly   196 DESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSER 260
            ..|....||..||..||.:||..|..||.:.:.|.::.|.||.:|...:.:||...:|..||:|:
Zfish   212 VCSVLIDILTNRSEAQLCKIFQYYSQLSKDGLAKDLEGELSGHLEDCLMTLVKAAWNKPAYFAEK 276

  Fly   261 LHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            |..:|.|:||.|.||||||||||||||..|.:.::..|||:|:..|:.:|.|||::.||.:.|
Zfish   277 LQHAMKGLGTDDNTLIRIIVSRSEIDLLKIMQEYKRMYGKTLQEAIQSETKGDYEKILLVLCG 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	29/63 (46%)
		Annexin	97..162	CDD:395139	21/64 (33%)
		Annexin	188..246	CDD:395139	22/57 (39%)
		Annexin	256..321	CDD:395139	35/64 (55%)
anxa1c	NP_861425.1	Annexin	42..106	CDD:278615	29/63 (46%)
		Annexin	113..178	CDD:278615	21/64 (33%)
		Annexin	197..262	CDD:278615	26/64 (41%)
		Annexin	272..337	CDD:278615	35/64 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860