DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa3b

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001007303.1	Gene:	anxa3b / 492336	ZFINID:	ZDB-GENE-041114-128	Length:	340	Species:	Danio rerio

Alignment Length:	310	Identity:	151/310 - (48%)
Similarity:	206/310 - (66%)	Gaps:	0/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSE 78
            ||.....|.|.||||.||||::|.||.||.:|:||.:|...||..|.:|::.:.|:.|..||:.:
Zfish    27 TVKEKTGFKPDEDAAELRKAIEGIGTTEKTLIDILCQRSNAQRQLICKAYQDNTGRSLCDDLEGD 91

  Fly    79 LGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSL 143
            ..|.|||:::||:||..:|...|...||.|.||.|..:||:|.:.|||.||.:...|....|::|
Zfish    92 THGDFEDILVALITPPAKFDCLEFKRAIKGAGTKESLLIELLASRSNYQIKAMRDAYLAETGRNL 156

  Fly   144 ESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRS 208
            ..|||.:.||.|::..::|.:|.|||:..||.|.|.|||:.|::|||.:||||||.|..||..||
Zfish   157 IDDLKSEVSGDFEKTLLNLAEGKRDESTNVDVAKAKADAKILYEAGEKKWGTDESKFIDILCHRS 221

  Fly   209 YQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDK 273
            ..||||..:||::|||..::::|:||.||.:|...:|||||.||...|.:||||.||.|.||.:.
Zfish   222 VAQLRQTLVEYKSLSGRTLQESIEREMSGCLEDILVAIVKCVKSVPAYLAERLHKSMKGTGTTES 286

  Fly   274 TLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            |||||||||||:||.|||..::..:|.||.|.|:.:||||:::|||.|.|
Zfish   287 TLIRIIVSRSELDLQDIKAEYKKLFGCSLYSTIESETSGDFRKALLKICG 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	28/63 (44%)
		Annexin	97..162	CDD:395139	25/64 (39%)
		Annexin	188..246	CDD:395139	29/57 (51%)
		Annexin	256..321	CDD:395139	38/64 (59%)
anxa3b	NP_001007303.1	Annexin	39..103	CDD:278615	28/63 (44%)
		Annexin	110..175	CDD:278615	25/64 (39%)
		Annexin	194..259	CDD:278615	32/64 (50%)
		Annexin	269..334	CDD:278615	38/64 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574841
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm6419
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760