DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa7

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_012821793.2	Gene:	anxa7 / 407959	XenbaseID:	XB-GENE-987772	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	328	Identity:	166/328 - (50%)
Similarity:	220/328 - (67%)	Gaps:	5/328 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSAEYYPFKCT-----PTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIA 60
            |.|:..:|:...     .|:..|..||.:.||..||||||||||||:||::::|.|...||.:|.
Frog   208 MYSSTQHPYAAAMTATQGTIKAAPNFDALSDAEKLRKAMKGFGTDEQAIVDVVANRSNDQRQKIK 272

  Fly    61 EAFKTSYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSN 125
            .||||:||||||.||||||.|..|::|:||..|...:.|..|:.|:.|.||.|..:||||||.:|
Frog   273 AAFKTAYGKDLIKDLKSELSGNVEELIIALFMPATYYDAWSLYHAMKGAGTQERVLIEILCTRTN 337

  Fly   126 YGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGE 190
            ..||.|...|:..||:.:|.|::.||||||:||.:|:.||||||||.|:...|..|||.|:.|||
Frog   338 SEIKNIVSCYKHEFGRDIEKDIRSDTSGHFERLLISMCQGNRDENQNVNLQQAEQDAQRLYQAGE 402

  Fly   191 GQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKID 255
            |:.|||||:||.:|.:||:.|||.:...|..:|..|:...|.|||||.:|.|..|:::|..::..
Frog   403 GKLGTDESSFNLVLASRSFPQLRAVAEAYARISKRDLISVIGREFSGYIEDGLKAVLQCAINRPA 467

  Fly   256 YFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLA 320
            :|:|||:.||.|.||.|.|||||||:||||||..||:|:...:.|||.:.|..||||||:|.|:|
Frog   468 FFAERLYRSMKGAGTDDSTLIRIIVTRSEIDLVQIKQAYVQMHQKSLSAAISSDTSGDYRRLLIA 532

  Fly   321 IVG 323
            |.|
Frog   533 IAG 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	40/63 (63%)
		Annexin	97..162	CDD:395139	30/64 (47%)
		Annexin	188..246	CDD:395139	28/57 (49%)
		Annexin	256..321	CDD:395139	38/64 (59%)
anxa7	XP_012821793.2	PTZ00009	<158..195	CDD:240227
		Annexin	238..302	CDD:395139	40/63 (63%)
		Annexin	309..374	CDD:395139	30/64 (47%)
		Annexin	392..458	CDD:395139	32/65 (49%)
		Annexin	468..533	CDD:395139	38/64 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm14095
Panther	1	1.100	-	-	O	PTHR10502
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.030