DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa11b

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_861431.1	Gene:	anxa11b / 353365	ZFINID:	ZDB-GENE-030707-5	Length:	485	Species:	Danio rerio

Alignment Length:	315	Identity:	175/315 - (55%)
Similarity:	223/315 - (70%)	Gaps:	2/315 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FKCTPTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLIS 73
            |:.|...:|.  .||:.|..:||||||||||||.||||:|..|...||:.:..|:||:|||||:.
Zfish   170 FRGTIKDFPG--ADPLRDVEVLRKAMKGFGTDENAIIELLGSRSNKQRVPLLAAYKTTYGKDLVR 232

  Fly    74 DLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQS 138
            ||||||.|.||:::||::....||.|.|..:||||.||||..:||||.:.||..||.|.:.|:..
Zfish   233 DLKSELTGHFEELVLAMLKSPAQFDASECKEAISGAGTDEACLIEILSSRSNAEIKEINRIYKAE 297

  Fly   139 FGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSI 203
            :|||||..:..||||||:||.|||.||||||.:.||.:.|..|||.||.|||.:.|||||.||:|
Zfish   298 YGKSLEDAISNDTSGHFRRLLVSLCQGNRDERETVDISMAKQDAQKLHSAGENKVGTDESQFNAI 362

  Fly   204 LITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGM 268
            |..||...|||:|.||:.:.|.||||:|.||.||.:|.|.:|:|||.|:...||:||||.:|.|.
Zfish   363 LCARSKPHLRQVFQEYQQMCGRDIEKSICREMSGDLESGMVAVVKCIKNTPAYFAERLHKAMQGA 427

  Fly   269 GTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            ||||:|||||:|||||:|:.||::.:...:||||.:.|.||||||||:.||.:.|
Zfish   428 GTKDRTLIRIMVSRSELDMLDIRQEYLRLFGKSLYTHISGDTSGDYKKLLLKLCG 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	39/63 (62%)
		Annexin	97..162	CDD:395139	35/64 (55%)
		Annexin	188..246	CDD:395139	32/57 (56%)
		Annexin	256..321	CDD:395139	40/64 (63%)
anxa11b	NP_861431.1	WWbp	<1..70	CDD:304964
		DUF1720	7..90	CDD:285440
		Annexin	184..249	CDD:278615	39/64 (61%)
		Annexin	256..321	CDD:278615	35/64 (55%)
		Annexin	339..405	CDD:278615	37/65 (57%)
		Annexin	415..480	CDD:278615	40/64 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574814
Domainoid	1	1.000	85	1.000	Domainoid score	I8121
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22759
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm6419
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.660