DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa5b

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_861422.2	Gene:	anxa5b / 337132	ZFINID:	ZDB-GENE-030131-9076	Length:	317	Species:	Danio rerio

Alignment Length:	310	Identity:	153/310 - (49%)
Similarity:	212/310 - (68%)	Gaps:	2/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSE 78
            ||.|...|:...||.:|.|||||.||||.:|:::|.:|...||.||..|:||.:||||::|||||
Zfish     6 TVKPQSGFNANSDAEVLYKAMKGLGTDEDSILQLLTKRSNGQRQEIKAAYKTLHGKDLVNDLKSE 70

  Fly    79 LGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSL 143
            |||||||:|:|||||...:....|.:||.|.||||:.:||||.:.|...:..|...|::...|.|
Zfish    71 LGGKFEDLIVALMTPPIIYEVTCLRNAIKGAGTDEKVLIEILASRSPNEVNEIKSSYKREHDKDL 135

  Fly   144 ESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRS 208
            |.|:.|||.|||:|:...|:|.:|  .||:.|:...:|||||..|||.::||||..|.:||..||
Zfish   136 EEDVTGDTGGHFERMLAVLLQASR--QQGIQESLIQSDAQALFAAGEQKYGTDEGQFITILGNRS 198

  Fly   209 YQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDK 273
            ...||::|.||..|||.:||::|:||.|||:::..||:|||.:|...||::.|:.:|.|.||.|:
Zfish   199 NAHLRRVFEEYRKLSGFEIEESIQRETSGSLQEILLAVVKCARSVPGYFADSLYAAMKGAGTDDQ 263

  Fly   274 TLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            |||||:|:|||:||.||:..|:.::..||...|:.||||||::.||.:.|
Zfish   264 TLIRIMVTRSEVDLLDIRAEFRKRFATSLHKMIQSDTSGDYRKTLLLLCG 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	39/63 (62%)
		Annexin	97..162	CDD:395139	26/64 (41%)
		Annexin	188..246	CDD:395139	29/57 (51%)
		Annexin	256..321	CDD:395139	33/64 (52%)
anxa5b	NP_861422.2	Annexin	18..82	CDD:278615	39/63 (62%)
		Annexin	94..154	CDD:278615	26/59 (44%)
		Annexin	171..236	CDD:278615	34/64 (53%)
		Annexin	246..311	CDD:278615	33/64 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574817
Domainoid	1	1.000	85	1.000	Domainoid score	I8121
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm6419
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760