DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and anxa1a

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_861423.1	Gene:	anxa1a / 334724	ZFINID:	ZDB-GENE-030131-6664	Length:	340	Species:	Danio rerio

Alignment Length:	310	Identity:	136/310 - (43%)
Similarity:	191/310 - (61%)	Gaps:	0/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSE 78
            ||.|...|:...|||:|.||:|..|.||..||:.|..|...||.:|..|::.:..|.|...||:.
Zfish    30 TVKPYAQFNAAADAAVLDKAIKAKGVDEPTIIDTLVHRSNAQRQQIKAAYQQATSKPLDVALKNA 94

  Fly    79 LGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSL 143
            |.|:.|||:|.|:....|:.|.:|..|:.|.||.|:.:||||.:.:|..|..|.|.|:|.:.|.|
Zfish    95 LKGELEDVVLGLLMTPAQYDAFQLKYAMKGAGTTEDTLIEILASRTNKEIGDIKQVYKQEYKKDL 159

  Fly   144 ESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRS 208
            |:|:|.||||.|:...:||.:..|.|:..|.:..|..||:||::|||.:.|||.|.|..||.:|:
Zfish   160 EADIKSDTSGDFRNALLSLCKATRSEDNIVKDDLADKDARALYEAGEKRKGTDCSVFIDILTSRN 224

  Fly   209 YQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDK 273
            ...||::|.:|...|..|:.|||..|..|.:|...:|:|||..:|..:|:|:|:.:|.|.|.:.|
Zfish   225 GPHLRKVFQQYNKYSKVDVAKAIDLELKGDIESCLIAVVKCVSNKPAFFAEKLNLAMKGSGYRGK 289

  Fly   274 TLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            .|.||:||||||||.:||:.:|.||||||...|:.||.|||:..|||:.|
Zfish   290 ILTRILVSRSEIDLANIKQEYQKKYGKSLYQDIQDDTKGDYETILLALCG 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	28/63 (44%)
		Annexin	97..162	CDD:395139	27/64 (42%)
		Annexin	188..246	CDD:395139	23/57 (40%)
		Annexin	256..321	CDD:395139	35/64 (55%)
anxa1a	NP_861423.1	Annexin	45..106	CDD:278615	25/60 (42%)
		Annexin	113..178	CDD:278615	27/64 (42%)
		Annexin	197..262	CDD:278615	27/64 (42%)
		Annexin	272..337	CDD:278615	35/64 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.760