DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and Anxa8

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001026824.1	Gene:	Anxa8 / 306283	RGDID:	1307719	Length:	327	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	162/304 - (53%)
Similarity:	210/304 - (69%)	Gaps:	1/304 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 FDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELGGKFED 85
            |:|..||..|.|||||.||:|:|||::|.:|..|||.:||::||..:||||...|||||.||||.
  Rat    21 FNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFER 85

  Fly    86 VILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGD 150
            :|:|||.|..::.|:|||||:.||||.|..|||||.:.:...::.|.:.||:.:|.:||.|::||
  Rat    86 LIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSTLEEDIQGD 150

  Fly   151 TSGHFKRLCVSLVQGNRDENQG-VDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQQLRQ 214
            |||:.:|:.|.|:||.||:..| ||...|:.|||.||.|||...||||..|.:||.|||...|.:
  Rat   151 TSGYLERILVCLLQGCRDDVSGFVDPGLALQDAQDLHAAGEKILGTDEMKFITILCTRSATHLMR 215

  Fly   215 IFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTLIRII 279
            :|.|||.::...||.:||.|..||:|:..|.:|||.::...||:|||:.:|.|.||.|.||||.|
  Rat   216 VFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKGAGTLDGTLIRNI 280

  Fly   280 VSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            ||||||||..||..||..|||:|.|.|.|||||.||.|||.:||
  Rat   281 VSRSEIDLNLIKSQFQKMYGKTLSSMIMGDTSGYYKTALLNLVG 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	37/63 (59%)
		Annexin	97..162	CDD:395139	30/64 (47%)
		Annexin	188..246	CDD:395139	27/57 (47%)
		Annexin	256..321	CDD:395139	43/64 (67%)
Anxa8	NP_001026824.1	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	21..92		41/70 (59%)
		Annexin	26..90	CDD:278615	37/63 (59%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	93..164		32/70 (46%)
		Annexin	97..162	CDD:278615	30/64 (47%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	177..249		33/71 (46%)
		Annexin	181..247	CDD:278615	32/65 (49%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	253..324		43/70 (61%)
		Annexin	257..322	CDD:278615	43/64 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335652
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860