DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and Anxa11

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001011918.1	Gene:	Anxa11 / 290527	RGDID:	1309911	Length:	503	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	173/333 - (51%)
Similarity:	223/333 - (66%)	Gaps:	16/333 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YP-FKCTPTVYPADP---------------FDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQ 55
            || :..:.|:.||.|               |||:.||.:||||||||||||:|||:.|..|...|
  Rat   168 YPGYSGSSTITPAVPPAQFGNRGTITDASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQ 232

  Fly    56 RLEIAEAFKTSYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEIL 120
            |.:|..:|||:||||||.||||||.|.||..|||||.....|...|:.:||.|.||||..:||||
  Rat   233 RQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGTDEACLIEIL 297

  Fly   121 CTLSNYGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQAL 185
            .:.||..|:.:.:.|:..|.|:||..::.||||||:||.:||.||||||:..||.:....|.|.|
  Rat   298 ASRSNEHIRELNRAYKTEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQEL 362

  Fly   186 HDAGEGQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCC 250
            :.|||.:.|||||.||:||.:||...|..:|.||:.::|.||||:|.||.||.:|:|.||:|||.
  Rat   363 YAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCL 427

  Fly   251 KSKIDYFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYK 315
            |:...:|:|||:.:|.|.||||:|||||:|||||:||.||:..::..|||||...|.|||||||:
  Rat   428 KNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYR 492

  Fly   316 RALLAIVG 323
            :.||.|.|
  Rat   493 KILLKICG 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	42/63 (67%)
		Annexin	97..162	CDD:395139	29/64 (45%)
		Annexin	188..246	CDD:395139	31/57 (54%)
		Annexin	256..321	CDD:395139	39/64 (61%)
Anxa11	NP_001011918.1	Annexin	202..267	CDD:395139	42/64 (66%)
		Annexin	274..339	CDD:395139	29/64 (45%)
		Annexin	357..423	CDD:395139	34/65 (52%)
		Annexin	433..498	CDD:395139	39/64 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335636
Domainoid	1	1.000	72	1.000	Domainoid score	I9085
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22759
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm9098
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.660