DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and Anxa10

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001129561.1	Gene:	Anxa10 / 26359	MGIID:	1347090	Length:	324	Species:	Mus musculus

Alignment Length:	308	Identity:	121/308 - (39%)
Similarity:	193/308 - (62%)	Gaps:	1/308 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSE 78
            |::||..|:|:.||.:|..|::||..::..:|:||.:|...||..||..:::.||:||||.||.:
Mouse    10 TIFPAPNFNPMMDAQMLGGALQGFDCNKDMLIDILTQRSNAQRQMIAGTYQSMYGRDLISVLKEQ 74

  Fly    79 LGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSL 143
            |...|::|::.||.|.|.:.|.||..|:.|.||||..:||||.:.:|..|..:.:.|...:..:|
Mouse    75 LSSHFKEVMVGLMYPPPSYDAHELWHAMKGPGTDENCLIEILASRTNGEIFQMREAYCLQYSNNL 139

  Fly   144 ESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRS 208
            :.|:..:|||||:...::|||.||:|... |.|.|..||..|.:|.:.:.|..::....||..:|
Mouse   140 QEDIYSETSGHFRDTLMNLVQANREEGYS-DPAMAAQDAMVLWEACQQKTGEHKTMMQMILCNKS 203

  Fly   209 YQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDK 273
            |.||..:|.|::|:||.|:..||...:.|..::..:|||:|.:.|..||:.:|:.::...|..:|
Mouse   204 YPQLWLVFQEFQNISGQDLVDAINDCYDGYFQELLVAIVRCIQDKPSYFAYKLYRAIHDFGFHNK 268

  Fly   274 TLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAI 321
            |:|||:::||||||..|::.::.::||||...||...||.|::|||||
Mouse   269 TVIRILIARSEIDLMTIRKRYKERFGKSLFHDIKNFASGHYEKALLAI 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	25/63 (40%)
		Annexin	97..162	CDD:395139	23/64 (36%)
		Annexin	188..246	CDD:395139	17/57 (30%)
		Annexin	256..321	CDD:395139	28/64 (44%)
Anxa10	NP_001129561.1	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	17..88		28/70 (40%)
		Annexin	22..86	CDD:278615	25/63 (40%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	89..160		26/70 (37%)
		Annexin	93..158	CDD:278615	23/64 (36%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	171..243		24/71 (34%)
		Annexin	175..241	CDD:278615	20/65 (31%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	247..318		31/70 (44%)
		Annexin	251..316	CDD:278615	28/64 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.720