DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and Anxa8

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_038501.2	Gene:	Anxa8 / 11752	MGIID:	1201374	Length:	327	Species:	Mus musculus

Alignment Length:	304	Identity:	160/304 - (52%)
Similarity:	211/304 - (69%)	Gaps:	1/304 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 FDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELGGKFED 85
            |:|..||..|.|||||.||:|:|||::|.:|..|||.:||::||..:||||...|||||.||||.
Mouse    21 FNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNVQRQQIAKSFKAQFGKDLTETLKSELSGKFER 85

  Fly    86 VILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGD 150
            :|:|||.|...:.|:|||||:.||||.|..|||||.:.:...::.|.:.||:.:|.:||.|::||
Mouse    86 LIVALMYPPYSYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSTLEEDIQGD 150

  Fly   151 TSGHFKRLCVSLVQGNRDENQG-VDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQQLRQ 214
            |||:.:|:.|.|:||:||:..| ||....:.||||||:|||...||||..|.:||.|||...|.:
Mouse   151 TSGYLERILVCLLQGSRDDVSGFVDPGLVLQDAQALHEAGEKIMGTDEMKFITILCTRSATHLMR 215

  Fly   215 IFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTLIRII 279
            :|.|||.::...||.:||.|..||:|:..|.:|||.::...||:|||:.:|.|.||:|.||||.|
Mouse   216 VFEEYEKIANKCIEDSIKSETHGSLEEAMLTVVKCTRNVHSYFAERLYYAMKGAGTRDGTLIRNI 280

  Fly   280 VSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            ||||||||..||..|:..|||:|.|.|..||||.||.|||.:||
Mouse   281 VSRSEIDLNLIKGQFKKMYGKTLSSMIMADTSGYYKTALLNLVG 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	37/63 (59%)
		Annexin	97..162	CDD:395139	30/64 (47%)
		Annexin	188..246	CDD:395139	27/57 (47%)
		Annexin	256..321	CDD:395139	41/64 (64%)
Anxa8	NP_038501.2	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	21..92		41/70 (59%)
		Annexin	26..90	CDD:306660	37/63 (59%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	93..164		32/70 (46%)
		Annexin	97..162	CDD:306660	30/64 (47%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	177..249		33/71 (46%)
		Annexin	181..247	CDD:306660	33/65 (51%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	253..324		41/70 (59%)
		Annexin	257..322	CDD:306660	41/64 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm8852
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760