DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AnxB9 and Anxa4

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001318049.1	Gene:	Anxa4 / 11746	MGIID:	88030	Length:	319	Species:	Mus musculus

Alignment Length:	310	Identity:	168/310 - (54%)
Similarity:	212/310 - (68%)	Gaps:	0/310 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSE 78
            ||..|..|:..|||..|||||||.||||.|||.|||.|...||.||..|:|::.|:|||.|||||
Mouse     7 TVKAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSE 71

  Fly    79 LGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSL 143
            |...||.|||.||||...:..|||..|:.|.||||..:||||.:.:...|:.|.|.|:|.:|:||
Mouse    72 LSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSL 136

  Fly   144 ESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRS 208
            |.|:..|||..|:|:.|||....|||...:|:|....|||.|::|||.:|||||..|.|||.:|:
Mouse   137 EEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRN 201

  Fly   209 YQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDK 273
            ...|..:|.||:.:|..|||::||.|.|||.|...||||||.:||..||:|||:.||.|:||.|.
Mouse   202 RNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDN 266

  Fly   274 TLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVG 323
            ||||::|||:|||:.||:.:|:..|||||.|:|||||||||::.||.:.|
Mouse   267 TLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCG 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	41/63 (65%)
		Annexin	97..162	CDD:395139	29/64 (45%)
		Annexin	188..246	CDD:395139	29/57 (51%)
		Annexin	256..321	CDD:395139	41/64 (64%)
Anxa4	NP_001318049.1	Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	14..85		44/70 (63%)
		Annexin	19..83	CDD:395139	41/63 (65%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	86..157		32/70 (46%)
		Annexin	90..155	CDD:395139	29/64 (45%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	169..241		36/71 (51%)
		Annexin	173..239	CDD:395139	33/65 (51%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	245..316		43/70 (61%)
		Annexin	249..314	CDD:395139	41/64 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm8852
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.860