DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB9 and Anxa11

DIOPT Version :9

Sequence 1:	NP_001262796.1	Gene:	AnxB9 / 42492	FlyBaseID:	FBgn0000083	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_038497.2	Gene:	Anxa11 / 11744	MGIID:	108481	Length:	503	Species:	Mus musculus

Alignment Length:	333	Identity:	172/333 - (51%)
Similarity:	223/333 - (66%)	Gaps:	16/333 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YP-FKCTPTVYPADP---------------FDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQ 55
            || :..:.|:.||.|               |||:.||.:||||||||||||:|||:.|..|...|
Mouse   168 YPGYSGSSTITPAVPPAQFGNRGTITAASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQ 232

  Fly    56 RLEIAEAFKTSYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEIL 120
            |.:|..:|||:||||||.||||||.|.||..|||||.....|...|:.:||.|.||||..:|||.
Mouse   233 RQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGTDEACLIEIF 297

  Fly   121 CTLSNYGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQAL 185
            .:.||..|:.:::.|:..|.|:||..::.||||||:||.:||.||||||:..||.:....|.|.|
Mouse   298 ASRSNEHIRELSRAYKTEFQKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQEL 362

  Fly   186 HDAGEGQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCC 250
            :.|||.:.|||||.||:||.:||...|..:|.||:.::|.||||:|.||.||.:|:|.||:|||.
Mouse   363 YAAGENRLGTDESKFNAILCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCL 427

  Fly   251 KSKIDYFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYK 315
            |:...:|:|||:.:|.|.||||:|||||:|||||:||.||:..::..|||||...|.|||||||:
Mouse   428 KNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYR 492

  Fly   316 RALLAIVG 323
            :.||.|.|
Mouse   493 KILLKICG 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB9	NP_001262796.1	Annexin	26..90	CDD:395139	42/63 (67%)
		Annexin	97..162	CDD:395139	28/64 (44%)
		Annexin	188..246	CDD:395139	31/57 (54%)
		Annexin	256..321	CDD:395139	39/64 (61%)
Anxa11	NP_038497.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..172		2/3 (67%)
		Cornifin	<120..185	CDD:280537	6/16 (38%)
		Annexin 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	198..269		47/70 (67%)
		Annexin	202..267	CDD:365936	42/64 (66%)
		Annexin 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	270..341		30/70 (43%)
		Annexin	274..339	CDD:365936	28/64 (44%)
		Annexin 3. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	353..425		35/71 (49%)
		Annexin	357..423	CDD:365936	34/65 (52%)
		Annexin 4. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01245	429..500		40/70 (57%)
		Annexin	433..498	CDD:365936	39/64 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22759
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	1	1.000	-	-		mtm8852
orthoMCL	1	0.900	-	-		OOG6_100522
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.660