Protein Alignment Cortactin and Abp1

DIOPT Version :10

• Sequence 1: NP_524426.2
• Gene: Cortactin / 42491
• FlyBaseID: FBgn0025865
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_001689246.2
• Gene: Abp1 / 5667958
• VectorBaseID: AGAMI1_005424
• Length: 432
• Species: Anopheles gambiae
• Alignment Length: 525
• Identity: 136/525 - (25%)
• Similarity: 196/525 - (37%)
• Gaps: 175/525 - (33%)

  Fly    83 YGYGGKFGVEKDRMDKSAVGHD---------YQGKVGKHASQKDYSDGFGGKF--------GVQE 130
            :||.|:..|.|    ....|.|         ..||:.....:.|.|:....||        |...
Mosquito    31 FGYEGQTNVLK----VQETGEDGISELAAELNSGKIQYAFLRVDNSETGIAKFVFINWQGEGAPI 91

  Fly   131 DRKD------KSAVGWDHVEKVEKHASQKDYATGFGGKFGVQSDRVDKSAVGWDHIEKVEK---- 185
            .||.      :...|..|...:..||:.:|         .|:..|:         :||::|
Mosquito    92 ARKGTCAKHVRDVTGLLHGAHITVHATNED---------DVEEARI---------LEKLQKVVVN 138

  Fly   186 HESQKDYS------KGFGGKFGVQEDRKDKSAVG----WDHKEAPQKHASQVDHKVKPVIEGAKP 240
            ....||||      |..|..:......|:.:...    |..:|..:||
Mosquito   139 DFKVKDYSQAIDSPKPVGTNYSRVNPTKEINPAERDEFWRKEEEEEKH----------------- 186

  Fly   241 SNLRAKFENLAKNSEEESRKRAEEQKRLREAKDKRDREEAAKKTVAENTPRTSTEAPPPKGSRAA 305
             .|:|::|.....:     ...||::|.||.::...||.||  |.|.:....|..:|....:|.|
Mosquito   187 -RLQAEYERKLNET-----VLLEEERRKREEREFEKREGAA--TAAASVSSASPVSPDRSYARQA 243

  Fly   306 ---IQTGRTGGIGNAISAFNQMQSPVSETPPARKEPIIIPKAQ--PVKIELEAKEEPTASTTSAA 365
               .:|.|...|...:.|..::.|        .|...:...||  |..|:.|..:|.|
Mosquito   244 SDQSKTEREREIKQVVEASAKVSS--------AKARFLNSTAQLSPTHIQAEVAQELT------- 293

  Fly   366 VAPTPTVVPAREPETAPVAKAAAPPPDVVPQIEVET-------VDTPP--RSEPQSPVYVPTPQP 421
                       ||..:|.  |:.....::.:::.|.       .||||  .:|.:.||
Mosquito   294 -----------EPPFSPT--ASFEERSIINELKAELESERQNGTDTPPALAAEEEPPV------- 338

  Fly   422 EVHAQVQVQPEPQPQADPEPVVEEEPLYQNQAEIKAASPLPPTNGTVSEAVAPSGTATVPEEAIY 486
                 |.| |..:|...||.|          .|:.|.....| |.|:
Mosquito   339 -----VMV-PAGEPVLSPEEV----------PEVAAGQYFDP-NATI------------------ 368

  Fly   487 ANSDNLADYLEDTGIHAIALYDYQAADDDEISFDPDDVITHIEKIDDGWWRGLCKN-RYGLFPAN 550
                :|:|  ||..|.|.||||||||||.||||||||:||||::||:|||:||..: .|||||||
Mosquito   369 ----DLSD--EDNMIRARALYDYQAADDSEISFDPDDIITHIDQIDEGWWQGLAPDGTYGLFPAN 427

  Fly   551 YVQVV 555
            ||:::
Mosquito   428 YVELI 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cortactin	NP_524426.2	HS1_rep	84..119	CDD:460497	10/43 (23%)
		HS1_rep	121..156	CDD:460497	10/48 (21%)
		HS1_rep	158..193	CDD:460497	7/38 (18%)
		HS1_rep	195..230	CDD:460497	6/38 (16%)
		rne	<327..489	CDD:236766	32/172 (19%)
		SH3_Cortactin	502..554	CDD:212892	39/52 (75%)
Abp1	XP_001689246.2	None