Protein Alignment Mvl and SMF3

DIOPT Version :9

• Sequence 1: NP_001262795.1
• Gene: Mvl / 42490
• FlyBaseID: FBgn0011672
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_013134.1
• Gene: SMF3 / 850721
• SGDID: S000004024
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 490
• Identity: 152/490 - (31%)
• Similarity: 238/490 - (48%)
• Gaps: 91/490 - (18%)

  Fly    75 RKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLH 139
            :|...|.|||.|:|:||:||||..:.:..||..||.:|:.:..:.:..:|:|.|..:||.:||..
Yeast     9 QKFAKFIGPGILVSVAYMDPGNYATSVSGGAQYKYTLLFSIFISNIFAVLLQCLCVKLGTITGYD 73

  Fly   140 LAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFL 204
            |||.|.....:...:.|::..|:|||.:|:.||:|||||:.:|..  :||..|||:|::|....|
Yeast    74 LAENCRHNLPKKLNYTLYLFAEVAIIATDLAEVVGTAIALQILFK--IPLTWGVLLTVLDVLVIL 136

  Fly   205 -FLDKYG-----LRKLEFLFGTLITIMAVSFGYE-YIVSAPNQGEVLEGMFVPWCSNCNSNVLLQ 262
             |....|     :|..||..|.|:....:.|..| :.||.|::.|:.:| |:|      ||::.:
Yeast   137 MFYTPNGQSLKKVRVFEFGVGILVIGTCICFVLELFKVSIPDKAELFKG-FLP------SNIIFK 194

  Fly   263 -------AVGVVGAVIMPHNLYLHSALVKSR--DIDRRQTKKVSEANFYFFIEASV-ALFVSFII 317
                   ::|::||.:|||:|||.|::||.|  |.|.::..||:.......|:.:: ..:...||
Yeast   195 EQQALYISLGILGATVMPHSLYLGSSIVKPRLHDYDLKKYGKVNARPSLSAIKYTLNYAYAELII 259

  Fly   318 NLFVVAVFAHG----MYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCT 378
            :||::|.|.:.    :.|.|.:...|.       |||.:             ..:||   .|...
Yeast   260 SLFLIATFVNSAILIVAGATLSGQPEA-------EDADL-------------LSIYK---LLVHY 301

  Fly   379 FGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSK 443
            ....|..|:.:.:|.:|||:.:..|.|||...||||....|.|...|.||.|||:|  ||.:...
Yeast   302 ISPAAGLIFALAMLCSGQSAGIICTLAGQIVSEGFLQWSLPPWATRLCTRLIAIVP--CLFVTLT 364

  Fly   444 MEDLTSMNDILN---AVMSLQLPFAAIPTIAFTS-------------------CAAIMGEF--VN 484
            |.: ..::||||   .|:||.||..:.|.|.||:                   ..||..|.  :|
Yeast   365 MGE-KGISDILNFSQVVLSLILPIVSAPLIYFTANRKLMVVHDENGVVRAPADVNAIADETTPLN 428

  Fly   485 GLGNKIV-----------SILLTIVVIGVNLYFVV 508
            ...:|||           |:.:..::..:|.|.|:
Yeast   429 SKHSKIVDFTNSRLLTYTSVFVWALIGSLNCYLVI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mvl	NP_001262795.1	nramp	75..479	CDD:162246	142/446 (32%)
		Nramp	97..486	CDD:279852	132/433 (30%)
SMF3	NP_013134.1	SLC5-6-like_sbd	10..402	CDD:382020	141/426 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I821
eggNOG	1	0.900	-	-		E1_COG1914
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I890
Isobase	1	0.950	-	0	Normalized mean entropy	S1387
OMA	1	1.010	-	-		QHG54724
OrthoFinder	1	1.000	-	-		FOG0000712
OrthoInspector	1	1.000	-	-		otm46851
orthoMCL	1	0.900	-	-		OOG6_100775
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2295
SonicParanoid	1	1.000	-	-		X461
TreeFam	1	0.960	-	-
	13	12.710