Protein Alignment Mvl and slc11a2

DIOPT Version :10

• Sequence 1: NP_001262795.1
• Gene: Mvl / 42490
• FlyBaseID: FBgn0011672
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001035460.1
• Gene: slc11a2 / 678623
• ZFINID: ZDB-GENE-021115-1
• Length: 547
• Species: Danio rerio
• Alignment Length: 495
• Identity: 311/495 - (62%)
• Similarity: 379/495 - (76%)
• Gaps: 10/495 - (2%)

  Fly    54 YFSDEKVLIPDDDSTNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWA 118
            || :|||.||||.:..: |||||||||||||||||||||||||||||:||||.|.:|:|||||.|
Zfish    36 YF-EEKVPIPDDGTEKL-FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLGA 98

  Fly   119 TVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLS 183
            |::|||:||||||||||||:||||:|.|.|..:||.|||:|:|:||||||||||||.|||:.|||
Zfish    99 TIIGLLLQRLAARLGVVTGMHLAEVCNRHYPTVPRIILWLMVELAIIGSDMQEVIGCAIALNLLS 163

  Fly   184 NKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMF 248
            ...:|||.||||||||||.|||||||||||||..||.||||||:||||||:..||:|..||:|||
Zfish   164 VGRIPLWAGVLITIVDTFVFLFLDKYGLRKLEAFFGFLITIMALSFGYEYVRVAPDQAAVLQGMF 228

  Fly   249 VPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFV 313
            :|:|..|..:.|.||||:|||||||||:||||||||||||:|...|:|.|||.|:|||:|:||||
Zfish   229 LPYCRGCGPSQLEQAVGIVGAVIMPHNIYLHSALVKSRDINRSNKKEVKEANKYYFIESSIALFV 293

  Fly   314 SFIINLFVVAVFAHGMYGKTNNDVVEVCKDK-SMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGC 377
            ||:||:|||||||...|||||.:|.:.|.:. |.:.|.   |..| |.|  ::.|:||||:.|||
Zfish   294 SFLINVFVVAVFAEAFYGKTNMEVSQQCNETGSPHTDL---FPAN-NET--LEVDIYKGGVVLGC 352

  Fly   378 TFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFS 442
            .||..|:|||.||||||||||||||||:|||.|||||||:|.|:.|||:||.|||.||..:|:|.
Zfish   353 FFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIFPTLLVAVFQ 417

  Fly   443 KMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFV 507
            .::.||.|||.||.:.|:|||||.||.:.|||..::|.:|.|||..||...||.::|..:|:|||
Zfish   418 DVQHLTGMNDFLNVLQSMQLPFALIPILTFTSLTSLMHDFANGLVWKIGGGLLILLVCAINMYFV 482

  Fly   508 VVQVENMEIKGGLLALVCIFAILYILFNLYLVIHMAACMG 547
            :|.|.::. ...|..|..:.:|.|:.|.:|||......:|
Zfish   483 IVYVTDLN-STVLYVLAALLSIAYLSFVIYLVWQCLLALG 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mvl	NP_001262795.1	nramp	75..479	CDD:162246	274/404 (68%)
slc11a2	NP_001035460.1	nramp	55..454	CDD:162246	274/404 (68%)