DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc93AB and DNAH17

DIOPT Version :9

Sequence 1:	NP_001262793.1	Gene:	Dhc93AB / 42485	FlyBaseID:	FBgn0013812	Length:	4496	Species:	Drosophila melanogaster
Sequence 2:	XP_011523718.1	Gene:	DNAH17 / 8632	HGNCID:	2946	Length:	4466	Species:	Homo sapiens

Alignment Length:	4489	Identity:	2687/4489 - (59%)
Similarity:	3405/4489 - (75%)	Gaps:	39/4489 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PDPRLELMGSFVIKSLKLKPEKWTRVVTVEEHKGIIKEFLDRNTPVVLIIILTPAAQLVPSTTFP 82
            ||.|||.:.......||.||:||::::..||:..:..||.::....||::.|..|..::|...||
Human     5 PDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGMIIPCLGFP 69

  Fly    83 LSQLKSKGVYFIKRYALPIPREDCGNFIIYGDLATRTIDQLSALVEEVLVPLLSNEDNYRNWPIM 147
            .| ||||||||||..:..|.:::....::|||::...:|||.|:|||||..||:..:|...||.:
Human    70 QS-LKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLLNQSENMAGWPQV 133

  Fly   148 VAQDVQKHVHSLKSTVHQVKGQVSGETILAMPVGVEKIVKAAKELVETEQCQFDLYLKSAIEGVV 212
            |::|:.|.||.||:.:..:.|::.|:|:|.:|..:..: ....|.:|......|..|..|||..:
Human   134 VSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSL-DGTLESMERIPSSLDNLLLHAIETTI 197

  Fly   213 IKWATQIHEVIKESPSNAFANGQNPTPHTEFTFWNNRLKNLSFIYDQLRNERIRAMALILEYSMS 277
            |.|:.||.:|:.:..:.|..:|.:|.|..||.||:.||.||..|::||...::..:..|||.:.|
Human   198 IDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKCIHEQLNRPKVNKIVEILEKAKS 262

  Fly   278 AYHPCFQTLFKNVVTALAEAKDITLYLNPLKRPLQHLEEIDFAECKPLLIPFMNTVGILWGNSRY 342
            .|.|..|.::.||...|.||.||.|||.||:..|:.:|:.||......:...::|:..:|..|.|
Human   263 CYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQADFTMLPTFIAKVLDTICFIWATSEY 327

  Fly   343 YCQSAKITVLLQEICNLIIHQAKRYLDPSSI---FHSDIDEAMQRLTLSIQILKFFRELFDYYKE 404
            |...|:|.|:|||.||.||...:.:|.|..:   ...:|:|.:..::|::.:||...:.:|:...
Human   328 YNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCV 392

  Fly   405 RLATFFTEPEERPPILWTFHPNSVFKRFNAFLERLTTIQWFFFTVIEFLKLEKVEIGGLRGRQLS 469
            .:..||.:.|   |:.|.|..:..|.|.|:|.:|:.||:..:.|.||||||||:|:||:||..|.
Human   393 NMKLFFKDKE---PVPWEFPSSLAFSRINSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLG 454

  Fly   470 TRITDVYVEFNQYFTAFASKSYDVLDPDDHEFDEDFKGFQTRILELDMKLAAILCQAFDDCHNLE 534
            :.:|.:|.|..:....||...||.|||.|..||.|:..|:.:|.:||.:||.|.||.||||..::
Human   455 SLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIK 519

  Fly   535 SIFKLISIVGSVLDRPKIKEEFTQRYAEIVRMLDDEMTICESIYDKQMELKKVGDNLYPNYNCPP 599
            |..||:.:.|.:::||.|..|...||:.::.:.|.|:...:.:||.||...:.|:....:.|.||
Human   520 SSAKLLYMCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPP 584

  Fly   600 VAAFIRWCHQLETRITAPVKNFKALQHEITKTEKSQEIVERYEILMVKLGSCKTQFFDDWAGQLD 664
            ||..::|..:|:.|:...:|:.|.::|.:....:::...::|:.:|..|...:.:.:..|...:|
Human   585 VAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVD 649

  Fly   665 GQIEENLKKSLIARDRRHNSLILNFSAALFSILREVHYMQQMKIEGIPQIAIDFAEKSDVFRSYT 729
            .....||.:.||.||...|.:.:|||.||.::||||.|:...:.:.||..|.....:::.||.:.
Human   650 QDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFV 714

  Fly   730 LNLEKTIDWYNSIQEGSSPVELRLIEPEIKMIDDLVEIGVNQLVWNSSDILSYLDKLRKPVAALQ 794
            .|||..:.|||.|:.....||..||:.|::.||..:......|.||...:..|:.::|:.:..||
Human   715 GNLELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQ 779

  Fly   795 NRMDHTQGNLRQIRKIMGVWAKQPLFERRDCKKDTVLSIDERPDRTSKRYAEIQAASIEIHKLLQ 859
            |||...:.|:..|.:.|..|:..|||||:|.||:.:|.:|.|....:||||.::.|.::|..::.
Human   780 NRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQAMVA 844

  Fly   860 DNMLQFDMESKQDDAVWLSYVDFVDNIVYENILKTVGVSVGYLAENMDPENNYAPLFESRLELVE 924
            :|...|..::.  ...|..||.::|::|.:...:.:..|:.:|.:||..:.:.|||||.|:||.|
Human   845 ENAELFRADTL--SLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEIRMELDE 907

  Fly   925 PNLVFVPSLDPEDPMGFNNMLIELMRDIMKMGSLIKRLKPNEKRNYVEMIKENQDIIDMRREILN 989
            ..|.|.|:|:.....||..::..|:.||..:..||.|| ..::.||...:::|.|:|:||.|:.:
Human   908 DGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRL-AKDRMNYKMDLEDNTDLIEMREEVSS 971

  Fly   990 GVDLVMEEASRFCRQFERYSYLWLDDREECMEYFLEYGRMLDPDEIELILIND--PNQPPPQPCQ 1052
            .|...|:||..:...||||||||.|:.:|.|:.||.||..:..:::: ...:|  |..|
Human   972 LVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLD-TWTDDTIPKTP------ 1029

  Fly  1053 PTIEAFREQIDNYESLFNEIEDIGPFQVFSSWFQVDVRPFRQALLNTVCKWGNMFKEHLVTTVTS 1117
            ||:..|:||||:||.|:.|:......:||..|.|.|.|||:||||:|:.:||.|||.||...||:
Human  1030 PTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTN 1094

  Fly  1118 SLMNLSHFIRKADEGLLQTVKEKDYEGLVSIMAYLMQVKERAAKTDEMFEPMQETIQLLKYYDMD 1182
            ||.:|..|::.|..||.:.:||.||:|||.:|.:||:||||.|.||.||||:::||:|||.|..:
Human  1095 SLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEE 1159

  Fly  1183 IPEEVNVLLQELPEQWANTKKIASTVKQQVSPLQATEVVSIRNKIALFESHIQLFREVFKTYDFF 1247
            :|||:::.||||||.||||||:|..||..|:||||.||..:|.|...||.....|||.|:....|
Human  1160 MPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPF 1224

  Fly  1248 RFDCYKPYLLMDRINDDMFLCESEMRDIQESGSLFEVNIPEFKVLKQCRKELRMLKQLWDYVNIV 1312
            .|....||..:::....:...|..|..:.:||.||||.:|::|.||.|.:|:|:||:|||.|.:|
Human  1225 SFSDPNPYKSLNKQQKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVV 1289

  Fly  1313 ATSIDDWKTTPWRKVDVENMDIECKKFAKDIRLLDKEMRPWDTFINLESTVKNMLTSLRAVGELQ 1377
            .|||:|||||.|:.::||.|||:|||||||:|.|||||:.||.|:.|::||||::||||||.|||
Human  1290 NTSIEDWKTTKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQ 1354

  Fly  1378 NPAIRERHWNQLMNSTKSLAALPKEVTVKFIMDHETTLAELLGLNLHECEEEVKNIVDKAVKEMS 1442
            |||||||||.|||.:|:          |||.|..|||||:||.||||..|:||:|||||||||..
Human  1355 NPAIRERHWQQLMQATQ----------VKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESG 1409

  Fly  1443 MEKILRDLNTTWTVMEFDHELHPRTGCNLLKASEELIETLEDNQVCLQNLITSKYIAHFLEEVST 1507
            |||:|:.|::||::|||.||.|||||..:||:||.|:||||||||.||||:.|||:||||:||::
Human  1410 MEKVLKALDSTWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTS 1474

  Fly  1508 WQNKLMIADQVITVWFEVQRTWTHLESIFMSSEDIRKQLPVDSDRFDNIDAEFRVLMDEMSVSSN 1572
            ||.||..||.||::||||||||:||||||:.|||||.|||.||.|||:|:.||:.||::...:.|
Human  1475 WQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPN 1539

  Fly  1573 VVASTNRSGLIERLEHLQKELTLCEKALAEYLETKRLAFPRFYFVSSADLLDVLSNGIQPEMVTK 1637
            ||.:|::.||..:||.|:|.|.:|||||||||||||||||||||||||||||:||||..|..|::
Human  1540 VVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSR 1604

  Fly  1638 HLTKLFDSIARLKFNRDESNE-INTASGMYAKDGEYVEFNELASIRGPVEVWLNRIQAAMRASLR 1701
            ||:|||||:.:|||..|.|:: :....|||:|:.||:.|::...:.|.|||||||:...|.::||
Human  1605 HLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLR 1669

  Fly  1702 HYVMEAVIAYEEKQREQWLFDYPAQVSLCGSQIWWSTEVNIAFSRLEEGYDNAIKDYYKKQISQL 1766
            |.:.|||:.||||.||||:.||||||:|..:||||:|||.:||:||||||:|||:||.|||||||
Human  1670 HEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENAIRDYNKKQISQL 1734

  Fly  1767 SLLITLLLGELSKGDRQKIMTICTIDVHSRDVVAKMIQAKLDSGSAFMWQSQLRHRFDDVEKDCF 1831
            ::|||||:|.|:.|||.|||||||||||:||||||||.||::|..||.||:|||||:|:.::.||
Human  1735 NVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESSQAFTWQAQLRHRWDEEKRHCF 1799

  Fly  1832 ANICDAEFQYCHEYLGNTPRLVITPLTDRCYITLTQSLHLVMGGAPAGPAGTGKTETTKDLGRAI 1896
            ||||||:.||.:||||||||||||||||||||||||||||:|||||||||||||||||||||||:
Human  1800 ANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKTETTKDLGRAL 1864

  Fly  1897 GISVYVFNCSEQMDYQSCGNIYKGLAQTGAWGCFDEFNRITVEVLSVVAVQVKSVQDAIRDKKDK 1961
            |..||||||||||||:||||||||||||||||||||||||:||||||:|||||.||||||.||..
Human  1865 GTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAVQVKCVQDAIRAKKKA 1929

  Fly  1962 FNFMGEMISCVPTVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFQDAR 2026
            |||:||:|..:||||||||||||||||.||||||||||||||||||||||||||||:||||.:||
Human  1930 FNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVVPDFELICEIMLMAEGFLEAR 1994

  Fly  2027 VLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPGRPEEEVLMRALRDFNIPKI 2091
            :||||||||||||||||||||||||||||||||||||||||||||.|.|::||||||||||||||
Human  1995 LLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKI 2059

  Fly  2092 ITDDMPVFMGLISDLFPALDVPRKRDQDFERTVKQAASDLLLQPEDNFILKVVQLEELLEVRHSV 2156
            :|||:|||||||.|||||||||||||.:||:.:||:..:|.||.||:|:||||||||||:|||||
Human  2060 VTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSV 2124

  Fly  2157 FIVGNAGTGKTQVWKTLLRTYQNIKRKPIFNDLNPKAVTNDELFGIINPATREWKDGLFSVLMRD 2221
            |||||||:||:||.|:|.:||||:||||:..||:|||||.|||||||||.||||||||||.:|||
Human  2125 FIVGNAGSGKSQVLKSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRD 2189

  Fly  2222 QANITGDQPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPSMRLLFEISNLRTATPA 2286
            .||||.|.||||:|||||||||||||||||||||||||||||||.|..:|||:||||:|||||||
Human  2190 LANITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPA 2254

  Fly  2287 TVSRAGILYINPQDLGWNPYVTSWVETRKIPAEKSNLVMLFDKYIPPSLETIRVRFKKITPVAEM 2351
            ||||||||||||.||||||.|:||:|.||:.:||:||::|||||:|..|:.:|..|||||||.|:
Human  2255 TVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEI 2319

  Fly  2352 AHIQMLCHLLNCFLIPANTPADCPKEWHELYFVFACIWAFGSAMFQDQAIDYRVEFSKWWVNEFK 2416
            ..||.:.:||.|.|.....|.|.|:|.:||||||.|.||||.||||||.:||||||||||:||||
Human  2320 TVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFK 2384

  Fly  2417 TVKFPPGGTVFDYFLDSETKTFLPWTEKIPKFELDSDLPLQAVIVHTSESIRLRFFLDLLMDKKH 2481
            |:|||..||:|||::|.:||.|||||:|:|.||||.|:||||.:|||:|:||:|:|:||||:|..
Human  2385 TIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSW 2449

  Fly  2482 PVMLVGNAGCGKTVLVNEKLQSL-SENYAVTTIPFNYYTTSEMLQKILEKPLEKKAGRNYGPPGN 2545
            |||||||||.||:||:.:||:|| ::||.|..:|||:||||.|||.:||||||||:||||||||.
Human  2450 PVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT 2514

  Fly  2546 KLLCYFVDDINMPEVDAYGTVQPHTLMRQHLDYGHWYDRNKLTLKDIHNCQYVACMNPTSGSFTI 2610
            |.|.||:||:||||||.||||.||||:|||:|:.|||||:|||||||||||||||||||||||||
Human  2515 KKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTSGSFTI 2579

  Fly  2611 NPRLQRHFCVLAVSFPGPESITVMYSSILAQHFANAEQKFTPIVTRMTPNIVAATIALHNKCLQV 2675
            :.||||||||.||||||.|::|.:|::||.||.  |.:..:..:.|::..:|||.:|||.|....
Human  2580 DSRLQRHFCVFAVSFPGQEALTTIYNTILTQHL--AFRSVSMAIQRISSQLVAAALALHQKITAT 2642

  Fly  2676 FLPTAIKSHYIFNLRDISNVFQGLLFSSTECLTGSTDLIRLWQHETQRVYSDKLTDDKDIDSFTK 2740
            |||||||.||:|||||:||:|||||||:.|.|....||:|||.|||:|||.||:.|:||.::..:
Human  2643 FLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHR 2707

  Fly  2741 MQHDIVKKSFEEIDESVIFDKPNIYCHFAGGIGDPKYMPIKGWPELHKLLQEAMSSYNDLVAAMN 2805
            :.....||.|:::.:.::|.||||:||||.|||||||:|:.....|:|||.:.:.|||::.|.||
Human  2708 VTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMN 2772

  Fly  2806 LVLFEDAMMHVCRINRILESPRGSALLVGVGGSGKQSLARLAAFISSLEVVQIQLKKGYGVNDLK 2870
            |||||||:.|:||||||||||||:||||||||||||||:||||:||.|:|.||.||||||:.|||
Human  2773 LVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLK 2837

  Fly  2871 NEFSGLYLKAGLKNVGIMFLMTDAQIPSEDFLVLINDMLATGEIPDLFPDDEIENIIAGVRNEVK 2935
            .:.:..|:||.:|||..:|||||:|:..|.|||||||:||:||||.||.:||:||||:.:|.:||
Human  2838 IDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVK 2902

  Fly  2936 GAGLVDTRENCWKFFIDRVRKQLKIVLCFSPVGSTLRVRSRKFPAIINATSINWFHEWPQEALIS 3000
            ..|:.||||.||||||::||:|||::||||||||.||||:|||||::|.|:|:||||||::||:|
Human  2903 SLGMNDTRETCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVS 2967

  Fly  3001 VAMNFLAQNKVLPENHRDSVAKFMAYVHTSVNTTSKVYLQNERRYNYTTPKSYLEQINLYIKLLN 3065
            |:..||.:.:.:|...:.|::.||:||||:||..|:|||..||||||||||::||||.||..||.
Human  2968 VSARFLEETEGIPWEVKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLA 3032

  Fly  3066 HKNEDLQSKIERLENGLEKLRSTALQVADLKVKLAVQEIELKEKNEAADALIEIVGIETEKVQTE 3130
            .|..:|.:|||||||||.||:|||.||.|||.|||:||.|||:|||:||.||::||||.|||..|
Human  3033 KKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKE 3097

  Fly  3131 KAVADEEEMKVALIADEVSKKQRDCEEDLLKAEPALMAAQDALNTLNKANLTELKSFGSPPGAVT 3195
            ||:||:||:||.:|...|::||:.||.||.||||||:|||:||:||||.||||||||||||.||.
Human  3098 KAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVV 3162

  Fly  3196 NVTAAVMVLLSQGGKVPKDRSWKAAKIAMAKVDTFLDSLINYDKENIHPEITKAIQPYLKDPEFE 3260
            |||||||:|.:.|||:|||:|||||||.|.|||||||||..:|||:|.....||.:||..:|.|:
Human  3163 NVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFD 3227

  Fly  3261 PEFVRSKSGAAAGLCAWVINIIKFYEVYCDVEPKRKALAAANAELAAAQDKLAGIKRKVMSLEEQ 3325
            |||:||||.||||||:|.|||::||||||||.|||:||..||||||.||:||:.||.|:..|...
Human  3228 PEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNAN 3292

  Fly  3326 LGKLTADFEKATADKLRCQQEADATQATIALANRLVGGLASENVRWAEAVNNFVKQGITLPGDIL 3390
            |..||:.||||||:|::||||||||...|.|||||||||||||:||||:|.||..||:||.||:|
Human  3293 LSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLCGDVL 3357

  Fly  3391 LITAFISYVGCFTKGFRIDLLLKMWTPFLKSIDPPIPTTENLDPLSLLTDDTTIAIWTNEGLPSD 3455
            ||:||:||||.|||.:|.:|:.|.|.|::.::..|||.|..||||||||||..:|.|.|:|||||
Human  3358 LISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVATWNNQGLPSD 3422

  Fly  3456 RMSIENATILSNSDRWPLMIDPQLQGVKWIKQKYGEDLKVIRLGQRSYLDIIEKSINAGCNVLIE 3520
            |||.||||||.|::||||::|.||||:||||.||..:||.|||||:||||:||::|:.|..:|||
Human  3423 RMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIE 3487

  Fly  3521 NIDENLDPVLDSLLGRNLIKKGKAIKIGDKEIEYNSNFRLILHTKLANPHYKPEMQAQTTLINFT 3585
            ||.|.:|||||.|||||.|||||.|||||||:||:..||||||||..|||||||||||.|||||.
Human  3488 NIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFL 3552

  Fly  3586 VTRDGLEDQLLAEVVKAERPDLEELKADLTKQQNDFKIMLKKLEDDLLSRLSSAGENILGDTALV 3650
            ||||||||||||.||..||||||:|||:|||.||:|||:||:|||.||:|||:|..|.|||||||
Human  3553 VTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALV 3617

  Fly  3651 ENLETTKSTASEIEQKVAEAKITSKEIDKAREYYRPAAARASLLYFILNELNTINPIYQFSLKAF 3715
            |||||||.||||||:||.|||||..:|::|||.|||||.||||||||||:||.|||:||||||||
Human  3618 ENLETTKHTASEIEEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAF 3682

  Fly  3716 SVVFQKAIAKAEPGDTLDLRVSNLIDCITYSVFQYTSRGLFECDKLIFASQMTFQILLMNEEVTS 3780
            :|||:|||.:..|.:.:..||.||.|.|||||:.||:|||||.|||||.:|:|||:|.|.:|:..
Human  3683 NVVFEKAIQRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNP 3747

  Fly  3781 AELDFLLRFPIKPHVTSPVDFLTNQSWGGICSLASKDEFRNLDRDIETSSKRWKKLVESELPEKE 3845
            .|||||||||.|..|.||||||.:|.||||.:|:..|||:|||.|||.|:||||||||||.||||
Human  3748 VELDFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKE 3812

  Fly  3846 KFPQEWKNKTALQRLCMIRALRPDRMTYALADFIEEKLGSKYVESRAMEFAKSYEEASPSTPIFF 3910
            .||:|||||||||:|||:|.|||||||||:.:|:|||:|||:||.|::||:|||||:||||.|||
Human  3813 IFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3877

  Fly  3911 ILSPGVNPLKDVEALGKQMGFSMDLGNFHNVSLGQGQEAIAEAAMDTAAKHGHWVV----LQNIH 3971
            ||||||:||||||||||::||::|.|..||||||||||.:||.|:|.||:.||||:    |||||
Human  3878 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQSWLQNIH 3942

  Fly  3972 LVRKWLPVLEKKLEYYAEDSHPDYRMFLSAEPASTPSAHIIPQGILESSIKITNEPPTGMLANLH 4036
            ||.:||..|:||||:|:..||.|||:|:|||||.:|..|||||||||::|||||||||||.||||
Human  3943 LVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLH 4007

  Fly  4037 KALDNFTQETLEMSGKEAEFKAILFSLCYFHAVVAERRKFGPQGWNKIYPFNVGDLNISVSVLYN 4101
            ||||.|||:||||..||.|||.:||:|||||||||||||||.||||:.||||.|||.||::||||
Human  4008 KALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINVLYN 4072

  Fly  4102 YLEANAKVPWEDLRYLFGEIMYGGHITDDWDRRLCITYLEEYMQPDLVDGELFLAPSFPAPPNTD 4166
            |||||.||||:||||||||||||||||||||||||.|||.||::.::::|::.|||.|..|||.|
Human  4073 YLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPGFQIPPNLD 4137

  Fly  4167 YQGYHTYVDEMMPAESPYLYGLHPNAEIGFLTTRAENIFRTVFEMQPRDAGAGGGATVTREDKVK 4231
            |:|||.|:||.:|.||||||||||||||||||..:|.:||||.||||::..:|.|..|:||:|||
Human  4138 YKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDSGAGTGVSREEKVK 4202

  Fly  4232 QIVDEIIEKLPEEFNMVEIMNKVEERTPYVIVAFQECERMNFLTSEMKRSLKELDLGLKGELTIT 4296
            .::|:|:||:||.|||.|||.|..|:||||:||||||||||.||:||:||||||:||||||||||
Human  4203 AVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTIT 4267

  Fly  4297 SDMEVLENSLFLDQVPPIWTQRAYPSLLGLNNWFIDLCLRLRELETWSTDFVLPSCVWLAGFFNP 4361
            :|:|.|..:||.|.||..|..|||||::||..|:.||.||:||||.|:|||.||:.|||||||||
Human  4268 TDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNP 4332

  Fly  4362 QSLLTAIMQSTARRNDLPLDKMCLQCDVTKKQKEEFTTAPRDGCCVHGIFMEGARWDIQQGIIME 4426
            ||.|||||||.||:|:.|||||||..:||||.:|:.|..||:|..|:|:||||||||.|.|:|.|
Human  4333 QSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAE 4397

  Fly  4427 SRLKELYPSMPVINIRAITQDKQDLRNMYECPVYKTRTRGPTTYVSNLNLKTKDKPGKWILAGVA 4491
            :|||||.|:||||.|:||..|:.:.:|:|||||||||.||| |||...|||||:|..|||||.||
Human  4398 ARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGP-TYVWTFNLKTKEKAAKWILAAVA 4461

  Fly  4492 LLLQ 4495
            ||||
Human  4462 LLLQ 4465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc93AB	NP_001262793.1	DHC_N1	204..782	CDD:285571	197/580 (34%)
		DHC_N2	1295..1708	CDD:285579	255/413 (62%)
		P-loop_NTPase	1841..2071	CDD:304359	206/229 (90%)
		P-loop_NTPase	2155..2290	CDD:304359	109/134 (81%)
		P-loop_NTPase	2448..2720	CDD:304359	182/272 (67%)
		P-loop_NTPase	2797..3064	CDD:304359	173/266 (65%)
		MT	3076..3419	CDD:289543	232/342 (68%)
		AAA_9	3447..3659	CDD:289547	158/211 (75%)
		Dynein_heavy	3799..4486	CDD:281078	480/690 (70%)
DNAH17	XP_011523718.1	DHC_N1	189..767	CDD:285571	197/580 (34%)
		DHC_N2	1272..1676	CDD:285579	255/413 (62%)
		P-loop_NTPase	1809..2039	CDD:304359	206/229 (90%)
		P-loop_NTPase	2123..2258	CDD:304359	109/134 (81%)
		AAA_7	2416..2687	CDD:289541	182/272 (67%)
		AAA_8	2764..3031	CDD:289546	173/266 (65%)
		MT	3043..3386	CDD:289543	232/342 (68%)
		AAA_9	3413..3626	CDD:289547	158/212 (75%)
		Dynein_heavy	3766..4456	CDD:281078	480/690 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	580	1.000	Domainoid score	I215
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	4993	1.000	Inparanoid score	I2
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56441
OrthoDB	1	1.010	-	-		D1463at33208
OrthoFinder	1	1.000	-	-		FOG0000396
OrthoInspector	1	1.000	-	-		otm42247
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	LDO	PTHR10676
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10120
SonicParanoid	1	1.000	-	-		X4281
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.870