DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc93AB and kl-5

DIOPT Version :9

Sequence 1:	NP_001262793.1	Gene:	Dhc93AB / 42485	FlyBaseID:	FBgn0013812	Length:	4496	Species:	Drosophila melanogaster
Sequence 2:	NP_001015499.4	Gene:	kl-5 / 26067054	FlyBaseID:	FBgn0267433	Length:	4559	Species:	Drosophila melanogaster

Alignment Length:	4593	Identity:	2457/4593 - (53%)
Similarity:	3235/4593 - (70%)	Gaps:	160/4593 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DPRLELMGSFVIKSLKLKPEKWTRVVTVEEHKGIIKEFLDRNTPVVLIIILTPAAQLVPSTTFPL 83
            |.|.|...:::.|:::||.:|||:::|..|.:.:|.|||:......:|..:....||.||.:||:
  Fly    12 DNRPEFFWNYLTKTMRLKLDKWTKMITTNEFRDVIIEFLNNPNKKRIIFTINSGGQLYPSYSFPV 76

  Fly    84 SQLKSKGVYFIKRYALP--IPREDCGNFIIYGDLATRTIDQLSALVEEVLVPLLSNEDNYRNWPI 146
             :.:.|..||| ||..|  :..|:..|.::.|||....:..||.|.:||..|||:|..|...|..
  Fly    77 -RPRYKVAYFI-RYLTPLHLTDENMLNSLLIGDLLPNPLANLSILCDEVFFPLLNNTVNQVGWTN 139

  Fly   147 MVAQDVQKHVHSLKSTVHQVKGQVSGETILAMPVGVEKIVKAAKELVETEQCQFDLYLKSAIEGV 211
            ::|.|::.....:::.:.|:||.|...||..:|:.::::::||..:...:....:..:|.::|.:
  Fly   140 VIANDMKTESQEMRNGIAQMKGLVINRTIFPLPICMDEVMQAAPAIAMGDISVVNPLMKHSLEFM 204

  Fly   212 VIKWATQIHEVIKESPSNAFANGQN-PTPHTEFTFWNNRLKNLSFIYDQLRNERIRAMALILEYS 275
            |:||...:.:::.........:.:| |.|...|:||.:||:||..:.:||.:.||:.:..:||..
  Fly   205 VVKWLDSVEDLVNIKAGEKIYSKENFPLPEAIFSFWESRLENLENLAEQLGDRRIKTIGFVLEKI 269

  Fly   276 MSAYHPCFQTLFKNVVTALAEAKDITLYLNPLKRPLQHLEEIDFAECKPLLIPFMNTVGILWGNS 340
            .|.:...::.:.:.|:.:||||:|||..|:||||.:...|..|..|.:..:.|.|.|:|::||:|
  Fly   270 QSIFEHSYRRIVELVLESLAEARDITKCLSPLKRKMDKFETNDMDENRSDIRPLMLTIGLVWGHS 334

  Fly   341 RYYCQSAKITVLLQEICNLIIHQAKRYLDPSSIFHSDIDEAMQRLTLSIQILKFFRELFD----- 400
            ||:.....:|:......|.:|....|.::|.|||..|:|||.::|.:::|.|::::.:::
  Fly   335 RYFHTLNNMTLFFNLFHNSLIDCVNRTVEPDSIFQGDVDEAYKKLDINMQHLEYYKLIYNECRNS 399

  Fly   401 YYKERLATFFTEPEERPPILWTFHPNSVFKRFNAFLERLTTIQWFFFTVIEFLKLEKVEIGGLRG 465
            ..|.::.|.|...:      ||:|.:.:|.|.:.||.||..::..|.||.:|.||||:.:|||:|
  Fly   400 LKKFKIGTTFNSQD------WTWHQDEIFGRLDKFLVRLEELKDLFNTVRDFQKLEKIVMGGLKG 458

  Fly   466 RQLSTRITDVYVEFNQYFTAFASKSYDVLDPDDHE--FDEDFKGFQTRILELDMKLAAILCQAFD 528
            ||::..:..:..|:|..:..:.:..|:.:|||...  |..|...|:.:...::..::....:..:
  Fly   459 RQITFALEKILEEYNSIYREWTNIQYNPIDPDAENSLFQRDRLSFKAKTDVMERMVSFQFEKGLE 523

  Fly   529 DCHNLESIFKLISIVGSVLDRPKIKEEFTQRYAEIVRMLDDE-MTICESIYDKQMELKKVGDNLY 592
            |.|:|       .:.||:|.||.||:........||...::| |.:.:...:.:.....:|.|..
  Fly   524 DTHDL-------LLAGSLLLRPIIKKHVEPLMHVIVDDFEEEIMCVKKEFINFKNVFTALGLNEL 581

  Fly   593 PNYNC-PPVAAFIRWCHQLETRITAPVKNFKALQHEITKTEKSQEIVERYEILMVKLGSCKTQFF 656
            |..:| |.|:..|.:..:|..||....|..:..::.:...|:...:.:.:.|::.::........
  Fly   582 PTDDCFPKVSGAISFLKKLRHRIIGLHKEHELYEYPLFDNERGGYVSDIFNIMVQEIDDFTKMLL 646

  Fly   657 DDWAGQLDGQIEENLKKSLIARDRRHNSLILNFSAALFSILREVHYMQQMKIEGIPQIAIDFAEK 721
            |.|..:....|::::..:||.:|.. |.|.:||:..|...|:::..::.:..:....:...|..:
  Fly   647 DKWTVECWQGIQQDITLTLIEKDEA-NELRVNFTERLIFALKDIKVVRLLGCDVSVNLTKFFCRE 710

  Fly   722 SDVFRSYTLNLEKTIDWYNSIQEGSSPVELRLIEPEIKMIDDLVEIGVNQLVWNSSDILSYLDKL 786
            .::::: .:.|.:..:|||...|.:.|.|.|||..|:.:|::.::..::.:.||:.. ..::..:
  Fly   711 DELWQA-RVKLMRIAEWYNDTFERAHPTEKRLIAAEMILIEEQMKPLLDFIKWNAFS-QRFIVMI 773

  Fly   787 RKPVAALQNRMDHTQGNLRQIRKIMGVWAKQPLFERRDCKKDTVLSIDERPDRTSKRYAEIQAAS 851
            .|.|..|.:|:...|.||..|::.:..|.|.|||:|:|.....:|..|.|....|.|.|......
  Fly   774 FKMVKYLHDRLVAAQENLEAIKESIRSWGKVPLFQRKDLNPALLLHTDPREPILSIRAANAADTQ 838

  Fly   852 IEIHKLLQDNM-LQFDM-------------ESKQDDAVW-------------------------- 876
            ..|..|:..|: |.||:             |.::.|.:|
  Fly   839 RLIDLLMYVNLKLFFDIPRRYSLPPGEHGEEDEESDGIWPPIISLSVMTSVKFKKKREVIDEEDD 903

  Fly   877 ---------------------------LS---------YVDFVDNIVYENILKTVGVSVGYLAEN 905
                                       ||         |..:||.|:.||::.:|..|..||...
  Fly   904 LEEFEEEQSESEEEIITPFHRYELLKGLSQEERALFREYEIYVDEIIAENLVDSVITSSTYLRME 968

  Fly   906 MDP--ENNYAPLFESRLELVEPNLVFVPSLDPEDPMGFNNMLIELMRDIMKMGSLIKRL--KPNE 966
            :|.  ||| .|:||..:||.|||:|:..:||.....||...:..::.|:..|.||:||:  .|.|
  Fly   969 VDNRYENN-TPIFEIFMELQEPNVVYFRNLDTSSKTGFAFFIETILDDMNNMMSLLKRVAQDPTE 1032

  Fly   967 KRN-----YVEMIKENQDIIDMRREILNGVDLVMEEASRFCRQFERYSYLWLDDREECMEYFLEY 1026
            ..|     :.:.:::..::...|.||:|.:.|.::......:.|..:|.||:.|:...:....::
  Fly  1033 VTNMNPYSFYDELQDKSELDKQRVEIMNKIKLALQAVRVHGKGFMEFSSLWIWDKSTYLSEVKKF 1097

  Fly  1027 GRMLDPDE------------IELILINDPNQPPPQPCQPTIEAFREQIDNYESLFNEIEDIGPFQ 1079
            ||.|..||            ::|:.:.          .|.:..::||:|.:..|.::|.....::
  Fly  1098 GRNLTLDERDAEADLEGSSGVKLLGLE----------YPPLSVYKEQLDKFIELQDQIRTWETYE 1152

  Fly  1080 VFSSWFQVDVRPFRQALLNTVCKWGNMFKEHLVTTVTSSLMNLSHFIRKADEGLLQTVKEKDYEG 1144
            .|..:.::::..|:.|:|:.|.:|.::||..|:..|.:||..|..|:.:|:..|...:::.|:||
  Fly  1153 DFFVFLRLNMTGFKVAVLSQVGQWISLFKLDLINRVKNSLKELQDFVDEANIVLKIELQKDDFEG 1217

  Fly  1145 LVSIMAYLMQVKERAAKTDEMFEPMQETIQLLKYYDMDIPEEVNVLLQELPEQWANTKKIASTVK 1209
            ||.|::.|.|:.|:....|.||:|::|.|.||:.|:.:..:.....:.|||:.|...|::|:|.|
  Fly  1218 LVKILSVLNQINEKQCIYDSMFDPLKEIIDLLRQYNYEFKDTELAQINELPDAWMKVKRLAATTK 1282

  Fly  1210 QQVSPLQATEVVSIRNKIALFESHIQLFREVFKTYDFFRFDCYKPYLLMDRINDDMFLCESEMRD 1274
            |.::|:|:.:|..|..:|.|.::....:|:.|.:..||...|...|.|:|..:.::...|...|.
  Fly  1283 QLIAPIQSYQVDLIEKRILLCDNMANTYRKKFLSKKFFFVPCLSCYELIDESDLELVALEERQRS 1347

  Fly  1275 IQESGSLFEVNIPEFKVLKQCRKELRMLKQLWDYVNIVATSIDDWKTTPWRKVDVENMDIECKKF 1339
            :.||..|||:..|:...::.||.:|:::|.:||:...:.::|:|||.|||:|:|:||||.|||||
  Fly  1348 LAESAVLFELQGPDPVKIELCRFDLKLVKIMWDFAITIQSTINDWKKTPWKKIDIENMDQECKKF 1412

  Fly  1340 AKDIRLLDKEMRPWDTFINLESTVKNMLTSLRAVGELQNPAIRERHWNQLMNSTKSLAALPKEVT 1404
            .:::|.|||.||.|:.||.:|:::||::||||||.||||||||:|||.:||.:||
  Fly  1413 GRELRGLDKAMRTWEPFIFMEASLKNLMTSLRAVTELQNPAIRDRHWIELMQTTK---------- 1467

  Fly  1405 VKFIMDHETTLAELLGLNLHECEEEVKNIVDKAVKEMSMEKILRDLNTTWTVMEFDHELHPRTGC 1469
            |||.||..|||.:|:.|||||.||||||||||:||||:|||.|||:.|.|..|||..::|.||..
  Fly  1468 VKFSMDDSTTLKDLIDLNLHEYEEEVKNIVDKSVKEMAMEKQLRDIATAWGTMEFGTDIHDRTSI 1532

  Fly  1470 NLLKASEELIETLEDNQVCLQNLITSKYIAHFLEEVSTWQNKLMIADQVITVWFEVQRTWTHLES 1534
            .||||||||||||||:|..|||:.:|||||.|..||..|||:|..|||:|..||||||.|.:|||
  Fly  1533 KLLKASEELIETLEDHQGQLQNMASSKYIAFFEHEVRLWQNRLSNADQIIGSWFEVQRKWQYLES 1597

  Fly  1535 IFMSSEDIRKQLPVDSDRFDNIDAEFRVLMDEMSVSSNVVASTNRSG--LIERLEHLQKELTLCE 1597
            ||:.|||||.|||.||.|||.||.||:.|:.:|:...|||.||||||  |.|.||.|.|.|.|||
  Fly  1598 IFIGSEDIRSQLPEDSRRFDYIDKEFKALLAQMNADRNVVRSTNRSGSKLYEHLEILLKMLLLCE 1662

  Fly  1598 KALAEYLETKRLAFPRFYFVSSADLLDVLSNGIQPEMVTKHLTKLFDSIARLKFNRDESNEINTA 1662
            |||.:|||||||::|||||||||||||:||||..|.:|.:|||||:||:.:|.......|    |
  Fly  1663 KALNDYLETKRLSYPRFYFVSSADLLDILSNGNNPALVARHLTKLYDSMGKLNLISGSKN----A 1723

  Fly  1663 SGMYAKD-GEYVEFNELASIRGPVEVWLNRIQAAMRASLRHYVMEAVIAYEEKQREQWLFDYPAQ 1726
            :||.||: .|||.|.|.....|.||||||||...||.:||..:..::..|:.|.|..|:|::|||
  Fly  1724 AGMVAKELEEYVPFLENCDCSGKVEVWLNRITDKMRDTLRDQLKRSLTFYDHKPRHVWIFEWPAQ 1788

  Fly  1727 VSLCGSQIWWSTEVNIAFSRLEEGYDNAIKDYYKKQISQLSLLITLLLGELSKGDRQKIMTICTI 1791
            .:|.|:||.|:||.|.||:::::.|:||:|||.||||:||:.||.||||:|:..:||||||||||
  Fly  1789 PALVGTQIMWTTETNDAFAKVQQRYENALKDYNKKQITQLNNLIILLLGDLTAAERQKIMTICTI 1853

  Fly  1792 DVHSRDVVAKMIQAKLDSGSAFMWQSQLRHRFDDVEKDCFANICDAEFQYCHEYLGNTPRLVITP 1856
            ||||||||..:|..|::..:||.||||||||:|....|||||||||:|:|.:|||||||||||||
  Fly  1854 DVHSRDVVGTIIAKKVEVQTAFQWQSQLRHRWDPKIDDCFANICDAQFRYDYEYLGNTPRLVITP 1918

  Fly  1857 LTDRCYITLTQSLHLVMGGAPAGPAGTGKTETTKDLGRAIGISVYVFNCSEQMDYQSCGNIYKGL 1921
            |||||||||||||||||||||||||||||||||||||||:|:.||||||||||||:|.|:|:|||
  Fly  1919 LTDRCYITLTQSLHLVMGGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGDIHKGL 1983

  Fly  1922 AQTGAWGCFDEFNRITVEVLSVVAVQVKSVQDAIRDKKDKFNFMGEMISCVPTVGIFITMNPGYA 1986
            |||||||||||||||:||||||||||||.:||||:.||..|:|:||.|:...|||:|||||||||
  Fly  1984 AQTGAWGCFDEFNRISVEVLSVVAVQVKCIQDAIKSKKQTFSFLGEHIALRTTVGVFITMNPGYA 2048

  Fly  1987 GRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFQDARVLARKFITLYTLCKELLSKQDHYDW 2051
            ||.|||||||||:||||||||||.||.||||||||||:||:||||||||||||||||||||||||
  Fly  2049 GRAELPENLKALYRPCAMVVPDFALISEIMLVAEGFQEARLLARKFITLYTLCKELLSKQDHYDW 2113

  Fly  2052 GLRAIKSVLVVAGSLKRGDPGRPEEEVLMRALRDFNIPKIITDDMPVFMGLISDLFPALDVPRKR 2116
            |||||||||||||:|:|.|..|||::||||||||||||||:|||:|||||||.||||||||||||
  Fly  2114 GLRAIKSVLVVAGALRRDDRQRPEDQVLMRALRDFNIPKIVTDDVPVFMGLIGDLFPALDVPRKR 2178

  Fly  2117 DQDFERTVKQAASDLLLQPEDNFILKVVQLEELLEVRHSVFIVGNAGTGKTQVWKTLLRTYQNIK 2181
            :.:||..:|::|.||.|||||.||||:||||||..|||||||:|.|||||::|||||.:||||.|
  Fly  2179 NPEFEAVIKRSALDLKLQPEDGFILKIVQLEELFAVRHSVFIIGFAGTGKSEVWKTLNKTYQNQK 2243

  Fly  2182 RKPIFNDLNPKAVTNDELFGIINPATREWKDGLFSVLMRDQANITGDQPKWIVLDGDIDPMWIES 2246
            |||.:||||||||||||||||:||:||||||||||:|||||||:.|..|||||||||||||||||
  Fly  2244 RKPHYNDLNPKAVTNDELFGIVNPSTREWKDGLFSILMRDQANLGGTGPKWIVLDGDIDPMWIES 2308

  Fly  2247 LNTVMDDNKVLTLASNERIALTPSMRLLFEISNLRTATPATVSRAGILYINPQDLGWNPYVTSWV 2311
            ||||||||||||||||||||||..|||||||::||||||||||||||||||||||||.|::.||:
  Fly  2309 LNTVMDDNKVLTLASNERIALTKEMRLLFEIASLRTATPATVSRAGILYINPQDLGWTPFIQSWL 2373

  Fly  2312 ETRKIPAEKSNLVMLFDKYIPPSLETIRVRFKKITPVAEMAHIQMLCHLLNCFLIPANTPADCPK 2376
            .||...:|.|.|.:|||||:||.|:..|.|.:.|||::::|.:||.|:||:..|.|.|.|.||||
  Fly  2374 GTRTNSSEVSMLNVLFDKYVPPLLDIFRTRLRSITPISDIARLQMTCYLLDSMLTPQNVPNDCPK 2438

  Fly  2377 EWHELYFVFACIWAFGSAMFQDQAIDYRVEFSKWWVNEFKTVKFPPGGTVFDYFLDSETKTFLPW 2441
            :|:|:||||..:|.|||::||||.||:..|||||::||:|.||||..||:|.:::|.|||.|.||
  Fly  2439 DWYEIYFVFCIVWGFGSSLFQDQIIDWSNEFSKWFLNEYKAVKFPLSGTIFSFYIDHETKKFFPW 2503

  Fly  2442 TEKIPKFELDSDLPLQAVIVHTSESIRLRFFLDLLMDKKHPVMLVGNAGCGKTVLVNEKLQSL-S 2505
            |..:|:||||.|||||:.:|:|:|:.|||||:|.|::..||:||:|.:|.|||:|:|.||.:| |
  Fly  2504 TNLVPQFELDMDLPLQSNLVNTAETTRLRFFMDTLIEADHPLMLIGPSGSGKTILMNAKLSALPS 2568

  Fly  2506 ENYAVTTIPFNYYTTSEMLQKILEKPLEKKAGRNYGPPGNKLLCYFVDDINMPEVDAYGTVQPHT 2570
            :.|:||.:|||:||||||||:||||||||||||||||.|||.:.|||||:||||||.|.||||||
  Fly  2569 DKYSVTNVPFNFYTTSEMLQRILEKPLEKKAGRNYGPIGNKRMIYFVDDMNMPEVDKYFTVQPHT 2633

  Fly  2571 LMRQHLDYGHWYDRNKLTLKDIHNCQYVACMNPTSGSFTINPRLQRHFCVLAVSFPGPESITVMY 2635
            |:||.:||.|||||.|:||:|||.|..||||||::|||||:||||||||..||:.|..:::..:.
  Fly  2634 LIRQFMDYHHWYDRQKMTLRDIHKCNIVACMNPSAGSFTIDPRLQRHFCSFAVNPPSQDALFHIL 2698

  Fly  2636 SSILAQHFANAEQKFTPIVTRMTPNIVAATIALHNKCLQVFLPTAIKSHYIFNLRDISNVFQGLL 2700
            :|||:||..|..|||...|.::..|:|...|.||.|.:..|||||||.||.||||||:|:|.|:|
  Fly  2699 NSILSQHMDNPIQKFDKAVIKLCENMVTTAITLHLKVVSSFLPTAIKFHYNFNLRDIANIFTGVL 2763

  Fly  2701 FSSTECLTGSTDLIRLWQHETQRVYSDKLTDDKDIDSFTKMQHDIVKKSFEEIDESVIFDKPNIY 2765
            :|::|....|..:||||.||..|||.|||.|..||:||.|:..|||:|..|.:::.|::.:|.||
  Fly  2764 YSNSETCPNSNQMIRLWIHECYRVYGDKLVDYTDINSFKKIVSDIVRKGIEGVNDDVVYAQPLIY 2828

  Fly  2766 CHFAGGIGDPKYMPIKGWPELHKLLQEAMSSYNDLVAAMNLVLFEDAMMHVCRINRILESPRGSA 2830
            ||||.|:.|.|||||.||..|..||.||...|||.:.|||||||:|||.|||||:|||||.||.|
  Fly  2829 CHFAKGLTDIKYMPISGWDRLKSLLDEAQDRYNDYIGAMNLVLFDDAMSHVCRISRILESSRGYA 2893

  Fly  2831 LLVGVGGSGKQSLARLAAFISSLEVVQIQLKKGYGVNDLKNEFSGLYLKAGLKNVGIMFLMTDAQ 2895
            ||:||||||||||.|||:|||||:|.||||.|.|.|:|||...:.||:|||:|.....|||||::
  Fly  2894 LLIGVGGSGKQSLTRLASFISSLDVFQIQLTKDYSVSDLKANIATLYMKAGVKTSACCFLMTDSE 2958

  Fly  2896 IPSEDFLVLINDMLATGEIPDLFPDDEIENIIAGVRNEVKGAGLVDTRENCWKFFIDRVRKQLKI 2960
            :..|.||||:||:||:|:|.:||||||:|||:..||||||..|:||.||||||:||::||..||:
  Fly  2959 VAREQFLVLVNDLLASGDIHELFPDDEVENIVNAVRNEVKQLGIVDNRENCWKYFIEKVRSLLKV 3023

  Fly  2961 VLCFSPVGSTLRVRSRKFPAIINATSINWFHEWPQEALISVAMNFLAQNKVLPENHRDSVAKFMA 3025
            ||||||||:|||||||||||::|.|:|:|||||||:||.||::.||::..|||:.....|:.|||
  Fly  3024 VLCFSPVGATLRVRSRKFPALVNCTTIDWFHEWPQQALESVSLRFLSEITVLPKELALPVSNFMA 3088

  Fly  3026 YVHTSVNTTSKVYLQNERRYNYTTPKSYLEQINLYIKLLNHKNEDLQSKIERLENGLEKLRSTAL 3090
            :||.:||..||:||.|.:|||||||||:||.|.||.|||:.|.:....:..||||||.||.|...
  Fly  3089 FVHKTVNDISKLYLANAKRYNYTTPKSFLELIALYSKLLHEKVKANLDRRLRLENGLIKLASCTK 3153

  Fly  3091 QVADLKVKLAVQEIELKEKNEAADALIEIVGIETEKVQTEKAVADEEEMKVALIADEVSKKQRDC 3155
            :|..|:..|.|||:|||.||:.||.||.:||.|.|||..|:|.|.:||..|..|.::|:.|.:.|
  Fly  3154 EVDALQDVLKVQEVELKIKNQEADNLIIVVGTENEKVSKERAFASKEEKNVRQIEEDVTAKAKLC 3218

  Fly  3156 EEDLLKAEPALMAAQDALNTLNKANLTELKSFGSPPGAVTNVTAAVMVLLSQGGKVPKDRSWKAA 3220
            |||.|||:|||:|||:|||||||.||||||||||||.||.:|..||:||.|..||:||||||||.
  Fly  3219 EEDFLKAQPALIAAQEALNTLNKNNLTELKSFGSPPDAVVSVCGAVLVLFSSKGKIPKDRSWKAC 3283

  Fly  3221 KIAMAKVDTFLDSLINYDKENIHPEITKAIQPYLKDPEFEPEFVRSKSGAAAGLCAWVINIIKFY 3285
            :..|..||.|||:||||||::|||::.||:|||:.|.||.||.:.:||.||||||:|||||.:||
  Fly  3284 RAFMGNVDKFLDNLINYDKKHIHPDVIKALQPYILDAEFSPEKILAKSSAAAGLCSWVININRFY 3348

  Fly  3286 EVYCDVEPKRKALAAANAELAAAQDKLAGIKRKVMSLEEQLGKLTADFEKATADKLRCQQEADAT 3350
            :||..||||.:||..:..|:..|:|||..:..::..|||||..|..::::|.|.|.:||.||..|
  Fly  3349 DVYLVVEPKERALLESEKEVKDARDKLTALNLRLTELEEQLNALQMEYDEALAKKQKCQDEASKT 3413

  Fly  3351 QATIALANRLVGGLASENVRWAEAVNNFVKQGI-TLPGDILLITAFISYVGCFTKGFRIDLLLKM 3414
            ..||.:||||:||||:|.:||.|:| ..:..|| .||||||:|:.|||||||||:.:|.:|..|:
  Fly  3414 AFTIDIANRLIGGLATEKIRWMESV-KVLTFGIQQLPGDILIISCFISYVGCFTRAYRQELQEKL 3477

  Fly  3415 WTPFLKSIDPPIPTTENLDPLSLLTDDTTIAIWTNEGLPSDRMSIENATILSNSDRWPLMIDPQL 3479
            |.|..|:..||||:|:.:||..::.||..||.|.|:||||||||.|||.||..|:|:||||||||
  Fly  3478 WMPAFKNSQPPIPSTDGVDPFEMICDDAQIAEWNNQGLPSDRMSAENAAILVQSERYPLMIDPQL 3542

  Fly  3480 QGVKWIKQKYGEDLKVIRLGQRSYLDIIEKSINAGCNVLIENIDENLDPVLDSLLGRNLIKKGKA 3544
            ||:||:|.|||..|.|:||.||:|||.:|::::.|..:|||||.||:||||:.||||.|||||..
  Fly  3543 QGIKWVKTKYGTGLVVLRLSQRNYLDQVERAVSNGSVLLIENIGENIDPVLNPLLGRQLIKKGTV 3607

  Fly  3545 IKIGDKEIEYNSNFRLILHTKLANPHYKPEMQAQTTLINFTVTRDGLEDQLLAEVVKAERPDLEE 3609
            :||||:||::||.||||||||||||||||||||||||||||||||||||||||||||.||||||.
  Fly  3608 LKIGDREIDFNSRFRLILHTKLANPHYKPEMQAQTTLINFTVTRDGLEDQLLAEVVKVERPDLEA 3672

  Fly  3610 LKADLTKQQNDFKIMLKKLEDDLLSRLSSAGENILGDTALVENLETTKSTASEIEQKVAEAKITS 3674
            ::..||:|||.|||.||.||||||:||||||:|:|.|..||.|||.||.||.|||.||||||||.
  Fly  3673 MRTRLTQQQNHFKITLKFLEDDLLARLSSAGDNVLEDVTLVMNLEKTKKTADEIEVKVAEAKITG 3737

  Fly  3675 KEIDKAREYYRPAAARASLLYFILNELNTINPIYQFSLKAFSVVFQKAIAKAEPGDTLDLRVSNL 3739
            .:||.|||.|||||.|||::|||||:|..||||||||||||:|||..|:.||...:.|..||.||
  Fly  3738 VQIDSAREAYRPAAERASIIYFILNDLFKINPIYQFSLKAFTVVFNNAMLKAMAAEKLKDRVENL 3802

  Fly  3740 IDCITYSVFQYTSRGLFECDKLIFASQMTFQILLMNEEVTSAELDFLLRFPIKPHVTSPVDFLTN 3804
            ||.||:..|.||||||||.|||||.:|:..|||:...||...|||||||||..|:.||...:||:
  Fly  3803 IDSITFCSFVYTSRGLFEQDKLIFLTQLCIQILVNLGEVEPTELDFLLRFPYMPNQTSNFTWLTH 3867

  Fly  3805 QSWGGICSLASKDEFRNLDRDIETSSKRWKKLVESELPEKEKFPQEWKNKTALQRLCMIRALRPD 3869
            ..||||.:|.::..|:.|::|||.|.|||||.|:||.||.||||.|||.|:|:||||::|.:|||
  Fly  3868 VGWGGIRALNNQAVFKGLEKDIEGSHKRWKKFVDSESPENEKFPGEWKGKSAIQRLCIMRCIRPD 3932

  Fly  3870 RMTYALADFIEEKLGSKYVESRAMEFAKSYEEASPSTPIFFILSPGVNPLKDVEALGKQMGFSMD 3934
            ||:||:..||||||||||:::|:|||::::||:||.|.|||:|||||:||||||.|||.:|||.|
  Fly  3933 RMSYAMRSFIEEKLGSKYIDARSMEFSRTFEESSPETHIFFVLSPGVDPLKDVEKLGKSLGFSFD 3997

  Fly  3935 LGNFHNVSLGQGQEAIAEAAMDTAAKHGHWVVLQNIHLVRKWLPVLEKKLEYYAEDSHPDYRMFL 3999
            ..|||:||||||||.:||.|::.|:::||||:|||||||.:|||.||||:|....:.|..||:||
  Fly  3998 HENFHSVSLGQGQEIVAENAIEIASQYGHWVILQNIHLVARWLPSLEKKMESSLSNVHTSYRLFL 4062

  Fly  4000 SAEPASTPSAHIIPQGILESSIKITNEPPTGMLANLHKALDNFTQETLEMSGKEAEFKAILFSLC 4064
            |||||..|:|||:|||||||:|||||||||||:||:|||||||:.|||||..||.||||||||||
  Fly  4063 SAEPAGDPAAHILPQGILESAIKITNEPPTGMMANIHKALDNFSDETLEMCSKETEFKAILFSLC 4127

  Fly  4065 YFHAVVAERRKFGPQGWNKIYPFNVGDLNISVSVLYNYLEANAKVPWEDLRYLFGEIMYGGHITD 4129
            ||||||||||||||||||:.||||||||.|||.|||||||||.:|||||||||||||||||||||
  Fly  4128 YFHAVVAERRKFGPQGWNRSYPFNVGDLTISVYVLYNYLEANTRVPWEDLRYLFGEIMYGGHITD 4192

  Fly  4130 DWDRRLCITYLEEYMQPDLVDGELFLAPSFPAPPNTDYQGYHTYVDEMMPAESPYLYGLHPNAEI 4194
            |||||||.|||||:|||:|:||||.....||||....|.|||.|:|:.:|:|||.|||||.||||
  Fly  4193 DWDRRLCRTYLEEFMQPELIDGELEYCQGFPAPGILKYTGYHNYIDDNLPSESPSLYGLHSNAEI 4257

  Fly  4195 GFLTTRAENIFRTVFEMQPR-DAGAGGGATVTREDKVKQIVDEIIEKLPEEFNMVEIMNKVEERT 4258
            |||||.:|.:||.|||:||| ..|:.||.||::||.:|.|:::|::|.|..||::|:|.:||:|:
  Fly  4258 GFLTTVSERLFRIVFELQPRMTGGSSGGETVSQEDIIKNIIEDILDKTPTPFNILELMGRVEDRS 4322

  Fly  4259 PYVIVAFQECERMNFLTSEMKRSLKELDLGLKGELTITSDMEVLENSLFLDQVPPIWTQRAYPSL 4323
            ||:|||||||||||.|.:|:||||.||||||||||||:|.||.|...|::||||..||:.||||:
  Fly  4323 PYIIVAFQECERMNNLMTELKRSLNELDLGLKGELTISSVMEDLMVCLYMDQVPEQWTKLAYPSM 4387

  Fly  4324 LGLNNWFIDLCLRLRELETWSTDFVLPSCVWLAGFFNPQSLLTAIMQSTARRNDLPLDKMCLQCD 4388
            |||.:||.||.|||||||.|..||.:||.:|||||||||||||||||.|||:|:.|||:|||.||
  Fly  4388 LGLQSWFSDLMLRLRELEGWVADFRMPSSIWLAGFFNPQSLLTAIMQQTARKNEWPLDRMCLNCD 4452

  Fly  4389 VTKKQKEEFTTAPRDGCCVHGIFMEGARWDIQQGIIMESRLKELYPSMPVINIRAITQDKQDLRN 4453
            ||||.|||.|||||:|..::|:||||||||::.|.|.::.||||:|:|||:.|:|:||||||::|
  Fly  4453 VTKKWKEELTTAPREGAYINGLFMEGARWDMKMGTIADAFLKELFPAMPVLYIKAVTQDKQDIKN 4517

  Fly  4454 MYECPVYKTRTRGPTTYVSNLNLKTKDKPGKWILAGVALLLQT 4496
            :|||||||.|.||| |:|...|||::::..||.||||.|||||
  Fly  4518 VYECPVYKIRLRGP-TFVWTFNLKSRERASKWTLAGVCLLLQT 4559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc93AB	NP_001262793.1	DHC_N1	204..782	CDD:285571	151/587 (26%)
		DHC_N2	1295..1708	CDD:285579	244/415 (59%)
		P-loop_NTPase	1841..2071	CDD:304359	196/229 (86%)
		P-loop_NTPase	2155..2290	CDD:304359	114/134 (85%)
		P-loop_NTPase	2448..2720	CDD:304359	166/272 (61%)
		P-loop_NTPase	2797..3064	CDD:304359	175/266 (66%)
		MT	3076..3419	CDD:289543	194/343 (57%)
		AAA_9	3447..3659	CDD:289547	154/211 (73%)
		Dynein_heavy	3799..4486	CDD:281078	463/687 (67%)
kl-5	NP_001015499.4	DHC_N1	197..763	CDD:285571	149/580 (26%)
		DHC_N2	1368..1770	CDD:285579	244/415 (59%)
		P-loop_NTPase	1903..2132	CDD:304359	196/228 (86%)
		P-loop_NTPase	2217..2352	CDD:304359	114/134 (85%)
		P-loop_NTPase	2510..2783	CDD:304359	166/272 (61%)
		P-loop_NTPase	2860..3127	CDD:304359	175/266 (66%)
		MT	3140..3480	CDD:289543	193/340 (57%)
		AAA_9	3509..3722	CDD:289547	154/212 (73%)
		Dynein_heavy	3864..4549	CDD:281078	463/685 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469754
Domainoid	1	1.000	536	1.000	Domainoid score	I266
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D117at7147
OrthoFinder	1	1.000	-	-		FOG0000396
OrthoInspector	1	1.000	-	-		otm47047
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750