DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc93AB and DNAH9

DIOPT Version :9

Sequence 1:	NP_001262793.1	Gene:	Dhc93AB / 42485	FlyBaseID:	FBgn0013812	Length:	4496	Species:	Drosophila melanogaster
Sequence 2:	XP_011522005.1	Gene:	DNAH9 / 1770	HGNCID:	2953	Length:	4501	Species:	Homo sapiens

Alignment Length:	4529	Identity:	2671/4529 - (58%)
Similarity:	3396/4529 - (74%)	Gaps:	72/4529 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AEAAAAAAA------GGPDPRLELMGSFVIKSLKLKPEKWTRVVTVEEHKGIIKEFLDRNT---- 61
            ||..||.||      .|.|.||.|:|::|..||:.....|.|.....|.:.:::.||.|:.
Human     4 AEERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGP 68

  Fly    62 -PVVLI------IILTPAAQLVPSTTFPLSQLKSKGVYFIKRYALPIPREDCGNFIIYGDLATRT 119
             |::::      :.:.|..::.|.:    ....:|.::|::....|...:.....::.|||....
Human    69 RPLLVVRPGPRGLAIRPGLEVGPES----GLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAP 129

  Fly   120 IDQLSALVEEVLVPLLSNEDNYRNWPIMVAQDVQKHVHSLKSTVHQVKGQVSGETILAMPVGVEK 184
            ::.|:||..||::|:|:||.|..|||.|:.:||::|.|||:..:..:..||.|:|:|.:|.|.||
Human   130 LEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEK 194

  Fly   185 IVKAAKELVETEQCQFDLYLKSAIEGVVIKWATQIHEVIKESPSNAFANGQNPTPHTEFTFWNNR 249
             ::.|....||.....|..:..|||..||||:.|:..|:|...|.....|:||||..|..||.:|
Human   195 -MEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSR 258

  Fly   250 LKNLSFIYDQLRNERIRAMALILEYSMSAYHPCFQTLFKNVVTALAEAKDITLYLNPLKRPLQHL 314
            .::|.:||:|||...:|.||.:|:...|:|.|.|:.::::||.|||||:||.::|.||:|.|:.|
Human   259 YEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLEAL 323

  Fly   315 EEIDFAECKPLLIPFMNTVGILWGNSRYYCQSAKITVLLQEICNLIIHQAKRYLDPSSIFHSDID 379
            |..:|.|.||.|.|.::.|.::|...:.|....::||||||||||:|.||..||.|..:..|:::
Human   324 ENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVE 388

  Fly   380 EAMQRLTLSIQILKFFRELFDYYKERLATFFTEPEERPPILWTFHPNSVFKRFNAFLERLTTIQW 444
            |:.::|.:....|.||::.|...:|.|.|:|.|.:|...  |.|..:.||.|.:.||.:|..::.
Human   389 ESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKE--WDFQSSLVFVRLDGFLGQLHVVEG 451

  Fly   445 FFFTVIEFLKLEKVEIGGLRGRQLSTRITDVYVEFNQYFTAFASKSYDVLDPDDHEFDEDFKGFQ 509
            ...|.::|.||.|||..|:||..||.::..::.||.:.:...:..|.|.|.....:|:.|...|.
Human   452 LLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFN 516

  Fly   510 TRILELDMKLAAILCQAFDDCHNLESIFKLISIVGSVLDRPKIKEEFTQRYAEIVRMLDDEMTIC 574
            .::.:||.:|..|..|||||...||..|||:.|.|::|:||.:..:.:.:|..:::|.:.::...
Human   517 QKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAV 581

  Fly   575 ESIYDKQM-ELKKVGDNLYP-NYNCPPVAAFIRWCHQLETRITAPVKNFKALQHEITKTEKSQEI 637
            ..||.:.: |..::|  ..| :.|.|.||..:||..:|..||..|..||..:.|...::.:.:.:
Human   582 RMIYSQHVQEEAELG--FSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRM 644

  Fly   638 VERYEILMVKLGSCKTQFFDDWAGQLDGQIEENLKKSLIARDRRHNSLILNFSAALFSILREVHY 702
            .::||.::..|...:|:.::||...:..:.:.||.:.|:.||.....:.:||:..|.|:|:|:.|
Human   645 QQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSY 709

  Fly   703 MQQMKIEGIPQIAIDFAEKSDVFRSYTLNLEKTIDWYNSIQEGSSPVELRLIEPEIKMIDDLVEI 767
            ::..:::.:|:.|.......|.:|....|||...:|||.:.:....||..|:|.|::.||..:..
Human   710 LEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRA 774

  Fly   768 GVNQLVWNSSDILSYLDKLRKPVAALQNRMDHTQGNLRQIRKIMGVWAKQPLFERRDCKKDTVLS 832
            ....|.|.:..|..|:.::...:..|:.|:..|:.|:.:|:.||..|. .|:|:.:|.|::::||
Human   775 AEETLNWKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWV-TPIFKTKDGKRESLLS 838

  Fly   833 IDERPDRTSKRYAEIQAASIEIHKLLQDNMLQFDMESKQDDAVWLSYVDFVDNIVYENILKTVGV 897
            :|:|.||..|.|..|:.:.::||.|:|:|:..|..:...:  :|.:||:.:||::.......:..
Human   839 LDDRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSN--IWKTYVNSIDNLLLNGFFLAIEC 901

  Fly   898 SVGYLAENMDPENNYAPLFESRLELVEPNLVFVPSLDPEDPMGFNNMLIELMRDIMKMGSLIKRL 962
            |:.||.||.:.:....|:||::|.|..|.|||.|||:.....||.:::..|:..|.::.||:.||
Human   902 SLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRL 966

  Fly   963 KP-NEKRNYVEMIKENQDIIDMRREILNGVDLVMEEASRFCRQFERYSYLWLDDREECMEYFLEY 1026
            .| |...:|...:....|:.:|||.::..|..:|.....:...|.:||||:::||:|.:..||.|
Human   967 SPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLY 1031

  Fly  1027 GRMLDPDEIELILIND--PNQPPPQPCQPTIEAFREQIDNYESLFNEIEDIGPFQVFSSWFQVDV 1089
            |.:|.|:||| ..:.|  |..|      |.:..|:.|||:||:|:.|:..:.|.:||..|.::|:
Human  1032 GHILTPEEIE-DHVEDGIPENP------PLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDI 1089

  Fly  1090 RPFRQALLNTVCKWGNMFKEHLVTTVTSSLMNLSHFIRKADEGLLQTVKEKDYEGLVSIMAYLMQ 1154
            |||:.:|||.:.:|..:||:|||..||.||.||..||:|::.|||:.|::.|::|||.||.:||.
Human  1090 RPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMA 1154

  Fly  1155 VKERAAKTDEMFEPMQETIQLLKYYDMDIPEEVNVLLQELPEQWANTKKIASTVKQQVSPLQATE 1219
            ||||.:.|||||||:::||:|||.|:.::||.|...|:||||:|.|.||:|.||||||:||||.|
Human  1155 VKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANE 1219

  Fly  1220 VVSIRNKIALFESHIQLFREVFKTYDFFRFDCYKPYLLMDRINDDMFLCESEMRDIQESGSLFEV 1284
            |..:|.:...|::..|.|.|.|.....||||...|:.::|..:.::...||.|..|.||.|||||
Human  1220 VTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISESASLFEV 1284

  Fly  1285 NIPEFKVLKQCRKELRMLKQLWDYVNIVATSIDDWKTTPWRKVDVENMDIECKKFAKDIRLLDKE 1349
            |:|::|.|:|||||:..||:|||.:.:|.:||..|:|||||.::||.|::|||:||:.||.||||
Human  1285 NVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKE 1349

  Fly  1350 MRPWDTFINLESTVKNMLTSLRAVGELQNPAIRERHWNQLMNSTKSLAALPKEVTVKFIMDHETT 1414
            :|.||.|..|||||.|.|:|||||.||||||||||||.|||.:|          .|.|.||.:||
Human  1350 VRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQAT----------GVSFTMDQDTT 1404

  Fly  1415 LAELLGLNLHECEEEVKNIVDKAVKEMSMEKILRDLNTTWTVMEFDHELHPRTGCNLLKASEELI 1479
            ||.||.|.||..|:||:.|||||.|||.|||.|::|.|||..|||.:|.||||...||.:.|:||
Human  1405 LAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDEDLI 1469

  Fly  1480 ETLEDNQVCLQNLITSKYIAHFLEEVSTWQNKLMIADQVITVWFEVQRTWTHLESIFMSSEDIRK 1544
            |.||||||.||||:.|||:|.||||||.||.||...|.||::|||||||||||||||..|||||.
Human  1470 EVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRA 1534

  Fly  1545 QLPVDSDRFDNIDAEFRVLMDEMSVSSNVVASTNRSGLIERLEHLQKELTLCEKALAEYLETKRL 1609
            |||.||.||:.||.:|:.|..:.....|||.:||:.||.|:||.:|..|.||||||||||:||||
Human  1535 QLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRL 1599

  Fly  1610 AFPRFYFVSSADLLDVLSNGIQPEMVTKHLTKLFDSIARLKFNRDESNE-INTASGMYAKDGEYV 1673
            |||||||:||:||||:||||..|:.|.:||:||||::|:::|..|.|.| ..|:.|||:|:.|||
Human  1600 AFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYV 1664

  Fly  1674 EFNELASIRGPVEVWLNRIQAAMRASLRHYVMEAVIAYEEKQREQWLFDYPAQVSLCGSQIWWST 1738
            .|:|.....|.||:|||.:...|:|::||.:.|.|.|||||.|||||||:||||:|..:||||:|
Human  1665 AFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTT 1729

  Fly  1739 EVNIAFSRLEEGYDNAIKDYYKKQISQLSLLITLLLGELSKGDRQKIMTICTIDVHSRDVVAKMI 1803
            ||.:||:||||||::|:|||||||::||..|||:|:|:||||||||||||||||||:||||||||
Human  1730 EVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMI 1794

  Fly  1804 QAKLDSGSAFMWQSQLRHRFDDVEKDCFANICDAEFQYCHEYLGNTPRLVITPLTDRCYITLTQS 1868
            ..|:|:..||:|.||||||:||..|.||||||||:|.|.:|||||||||||||||||||||||||
Human  1795 AQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQS 1859

  Fly  1869 LHLVMGGAPAGPAGTGKTETTKDLGRAIGISVYVFNCSEQMDYQSCGNIYKGLAQTGAWGCFDEF 1933
            |||.|.|||||||||||||||||||||:||.||||||||||||:|||||||||||||||||||||
Human  1860 LHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEF 1924

  Fly  1934 NRITVEVLSVVAVQVKSVQDAIRDKKDKFNFMGEMISCVPTVGIFITMNPGYAGRTELPENLKAL 1998
            |||:|||||||||||||:||||||||..|:|:||.||..|:||||||||||||||||||||||:|
Human  1925 NRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSL 1989

  Fly  1999 FRPCAMVVPDFELICEIMLVAEGFQDARVLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVA 2063
            ||||||||||||||||||||||||.:|:.|||||||||.||||||||||||||||||||||||||
Human  1990 FRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVA 2054

  Fly  2064 GSLKRGDPGRPEEEVLMRALRDFNIPKIITDDMPVFMGLISDLFPALDVPRKRDQDFERTVKQAA 2128
            ||||||||.|||::||||:|||||||||:|||||:|||||.||||||||||:||.:||..|::|.
Human  2055 GSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAI 2119

  Fly  2129 SDLLLQPEDNFILKVVQLEELLEVRHSVFIVGNAGTGKTQVWKTLLRTYQNIKRKPIFNDLNPKA 2193
            .||.||.||||:||||||||||.||||||:||.|||||:||.::|.:|||.:||:|::.||||||
Human  2120 VDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKA 2184

  Fly  2194 VTNDELFGIINPATREWKDGLFSVLMRDQANITGDQPKWIVLDGDIDPMWIESLNTVMDDNKVLT 2258
            ||||||||||||||.||||||||.:||:.||||.|.||||:||||||||||||||||||||||||
Human  2185 VTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLT 2249

  Fly  2259 LASNERIALTPSMRLLFEISNLRTATPATVSRAGILYINPQDLGWNPYVTSWVETRKIPAEKSNL 2323
            |||||||.|.|:|:||||||:|||||||||||||||||||.||||||.|:||:|.|:|..|::||
Human  2250 LASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANL 2314

  Fly  2324 VMLFDKYIPPSLETIRVRFKKITPVAEMAHIQMLCHLLNCFLIPANTPADCPKEWHELYFVFACI 2388
            .:|||||:|..|:|:|.|||||.|:.|.:.:||:||||.|.|...:.|||||||.:|.|||||.|
Human  2315 TILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAI 2379

  Fly  2389 WAFGSAMFQDQAIDYRVEFSKWWVNEFKTVKFPPGGTVFDYFLDSETKTFLPWTEKIPKFELDSD 2453
            ||||.||.|||.:|||.||||||:.||||||||..||:|||::|.|||.|.||::.:|:||.|.:
Human  2380 WAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPE 2444

  Fly  2454 LPLQAVIVHTSESIRLRFFLDLLMDKKHPVMLVGNAGCGKTVLVNEKLQSLS-ENYAVTTIPFNY 2517
            :||||.:|||||:||:.:|::.||.::.||||||.||.||:|||..||.||. |.|.|..:||||
Human  2445 MPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNY 2509

  Fly  2518 YTTSEMLQKILEKPLEKKAGRNYGPPGNKLLCYFVDDINMPEVDAYGTVQPHTLMRQHLDYGHWY 2582
            ||||.|||.:|||||||||||||||||||.|.||:||:|||||||||||||||::||||||||||
Human  2510 YTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWY 2574

  Fly  2583 DRNKLTLKDIHNCQYVACMNPTSGSFTINPRLQRHFCVLAVSFPGPESITVMYSSILAQHFANAE 2647
            ||:||:||:|.|.|||:|||||:|||||||||||||.|..:||||.::::.:||.||.||....
Human  2575 DRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLG- 2638

  Fly  2648 QKFTPIVTRMTPNIVAATIALHNKCLQVFLPTAIKSHYIFNLRDISNVFQGLLFSSTECLTGSTD 2712
             .|...:.:..|.::...:|.|.|....||||.||.||||||||.:|:|||:||||.||:..:.|
Human  2639 -NFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWD 2702

  Fly  2713 LIRLWQHETQRVYSDKLTDDKDIDSFTKMQHDIVKKSFEEIDESV-IFDKPNIYCHFAGGIGDPK 2776
            ||||:.||:.|||.||:.::||.|.|.|:|.:::||:|::|::.| ....||:|||||.|||:||
Human  2703 LIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPK 2767

  Fly  2777 YMPIKGWPELHKLLQEAMSSYNDLVAAMNLVLFEDAMMHVCRINRILESPRGSALLVGVGGSGKQ 2841
            |||::.|..|.:.|.||:.::|::...|:||||||||.|||.||||||||||:||||||||||||
Human  2768 YMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQ 2832

  Fly  2842 SLARLAAFISSLEVVQIQLKKGYGVNDLKNEFSGLYLKAGLKNVGIMFLMTDAQIPSEDFLVLIN 2906
            ||.||||||||::|.||.|:|||.:.|.|.:.:.|.||||:||:..:|||||||:..|.||||||
Human  2833 SLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLIN 2897

  Fly  2907 DMLATGEIPDLFPDDEIENIIAGVRNEVKGAGLVDTRENCWKFFIDRVRKQLKIVLCFSPVGSTL 2971
            |:||:||||||:.|||:||||:.||||||..||||.|||||||||||:|:|||:.|||||||:.|
Human  2898 DLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKL 2962

  Fly  2972 RVRSRKFPAIINATSINWFHEWPQEALISVAMNFLAQNKVLPENHRDSVAKFMAYVHTSVNTTSK 3036
            ||||||||||:|.|:|:|||||||:||.||::.||...:.:....:.|::||||:||||||.||:
Human  2963 RVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQ 3027

  Fly  3037 VYLQNERRYNYTTPKSYLEQINLYIKLLNHKNEDLQSKIERLENGLEKLRSTALQVADLKVKLAV 3101
            .||.||:|||||||||:||.|.||..||:...::|:.|.|||||||.||.||:.||.|||.|||.
Human  3028 SYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAA 3092

  Fly  3102 QEIELKEKNEAADALIEIVGIETEKVQTEKAVADEEEMKVALIADEVSKKQRDCEEDLLKAEPAL 3166
            ||:|||:|||.||.||::||:||:||..|||:|||||.|||:|..||.:||:||||||.||||||
Human  3093 QEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPAL 3157

  Fly  3167 MAAQDALNTLNKANLTELKSFGSPPGAVTNVTAAVMVLLSQGGKVPKDRSWKAAKIAMAKVDTFL 3231
            .|||.|||||||.||||||||||||.||:||:||||||::..|:|||||||||||:.|||||.||
Human  3158 TAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFL 3222

  Fly  3232 DSLINYDKENIHPEITKAIQPYLKDPEFEPEFVRSKSGAAAGLCAWVINIIKFYEVYCDVEPKRK 3296
            |||||::|||||....|||:|||:||||.||||.:||.||||||:|||||::||||:|||||||:
Human  3223 DSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQ 3287

  Fly  3297 ALAAANAELAAAQDKLAGIKRKVMSLEEQLGKLTADFEKATADKLRCQQEADATQATIALANRLV 3361
            ||..|.|:|.|||:|||.||.|:..|.|.|.||||.|||||||||:|||||:.|..||:||||||
Human  3288 ALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLV 3352

  Fly  3362 GGLASENVRWAEAVNNFVKQGITLPGDILLITAFISYVGCFTKGFRIDLLLKMWTPFLKSIDPPI 3426
            |||||||||||:||.||.:|..||.||||||||||||:|.|||.:|..||.:.|.|:|..:..||
Human  3353 GGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPI 3417

  Fly  3427 PTTENLDPLSLLTDDTTIAIWTNEGLPSDRMSIENATILSNSDRWPLMIDPQLQGVKWIKQKYGE 3491
            |.|..||||.:|.||..:|.|.|||||:||||:||||||.|.:|||||:||||||:||||.||||
Human  3418 PVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGE 3482

  Fly  3492 DLKVIRLGQRSYLDIIEKSINAGCNVLIENIDENLDPVLDSLLGRNLIKKGKAIKIGDKEIEYNS 3556
            ||:|.::||:.||.|||:::.||..|||||::|::||||..||||.:||||:.|||||||.|||.
Human  3483 DLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEYNP 3547

  Fly  3557 NFRLILHTKLANPHYKPEMQAQTTLINFTVTRDGLEDQLLAEVVKAERPDLEELKADLTKQQNDF 3621
            .||||||||||||||:||:|||.||||||||||||||||||.||..||||||:||:|||||||.|
Human  3548 KFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGF 3612

  Fly  3622 KIMLKKLEDDLLSRLSSAGENILGDTALVENLETTKSTASEIEQKVAEAKITSKEIDKAREYYRP 3686
            ||.||.|||.||||||||..|.||:|.||||||.||.||:|:|:||.|||:|..:|::|||:|||
Human  3613 KITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRP 3677

  Fly  3687 AAARASLLYFILNELNTINPIYQFSLKAFSVVFQKAIAKAEPGDTLDLRVSNLIDCITYSVFQYT 3751
            |||||||||||:|:|:.|:|:|||||||||:|||||:.:|.|.::|..||:||||.||:||:|||
Human  3678 AAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYT 3742

  Fly  3752 SRGLFECDKLIFASQMTFQILLMNEEVTSAELDFLLRFPIKPHVTSPVDFLTNQSWGGICSLASK 3816
            .|||||||||.:.:|:||||||||.||.:.|||||||.|::....|||:||::|:||.:..|:|.
Human  3743 IRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSM 3807

  Fly  3817 DEFRNLDRDIETSSKRWKKLVESELPEKEKFPQEWKNKTALQRLCMIRALRPDRMTYALADFIEE 3881
            :||.|||||||.|:|.|||.||||.|||||.|||||||||||||||:||:|||||||||.||:||
Human  3808 EEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEE 3872

  Fly  3882 KLGSKYVESRAMEFAKSYEEASPSTPIFFILSPGVNPLKDVEALGKQMGFSMDLGNFHNVSLGQG 3946
            |||||||..||::||.|:||:.|:||:||||||||:||||||:.|:::|::.:..||||||||||
Human  3873 KLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQG 3937

  Fly  3947 QEAIAEAAMDTAAKHGHWVVLQNIHLVRKWLPVLEKKLEYYAEDSHPDYRMFLSAEPASTPSAHI 4011
            ||.:||||:|.|||.||||:|||||||.|||..||||||.::|:|||::|:|:|||||.:|..||
Human  3938 QEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHI 4002

  Fly  4012 IPQGILESSIKITNEPPTGMLANLHKALDNFTQETLEMSGKEAEFKAILFSLCYFHAVVAERRKF 4076
            |||||||:||||||||||||.||||||||||||:||||..:|.|||:|||:||||||||||||||
Human  4003 IPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKF 4067

  Fly  4077 GPQGWNKIYPFNVGDLNISVSVLYNYLEANAKVPWEDLRYLFGEIMYGGHITDDWDRRLCITYLE 4141
            ||||||:.||||.|||.|||:||||:||||||||::||||||||||||||||||||||||.|||.
Human  4068 GPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLG 4132

  Fly  4142 EYMQPDLVDGELFLAPSFPAPPNTDYQGYHTYVDEMMPAESPYLYGLHPNAEIGFLTTRAENIFR 4206
            |:::|::::|||.|||.||.|.|.||.|||.|:|..:|.||||||||||||||||||..:|.:||
Human  4133 EFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFR 4197

  Fly  4207 TVFEMQPRDAGAGGGATVTRED---------------KVKQIVDEIIEKLPEEFNMVEIMNKVEE 4256
            ||.|:||||:.|..||..|||:               |||.:::||:|::.:|||:.|:|.||||
Human  4198 TVLELQPRDSQARDGAGATREEKLFSWRWHCVLTIQGKVKALLEEILERVTDEFNIPELMAKVEE 4262

  Fly  4257 RTPYVIVAFQECERMNFLTSEMKRSLKELDLGLKGELTITSDMEVLENSLFLDQVPPIWTQRAYP 4321
            ||||::||||||.|||.||.|::|||:||:||||||||:||.||.|:|:|:.|.||..|.:||||
Human  4263 RTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYP 4327

  Fly  4322 SLLGLNNWFIDLCLRLRELETWSTDFVLPSCVWLAGFFNPQSLLTAIMQSTARRNDLPLDKMCLQ 4386
            |..||..||.||..|::|||.|:.||.:||.|||.|||||||.||||||||||:|:.|||:|.||
Human  4328 STAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQ 4392

  Fly  4387 CDVTKKQKEEFTTAPRDGCCVHGIFMEGARWDIQQGIIMESRLKELYPSMPVINIRAITQDKQDL 4451
            ||:|||.:|||.:.||:|..:||:|||||.||.|.|||.|::||:|.|.|||:.|:||..||||.
Human  4393 CDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDC 4457

  Fly  4452 RNMYECPVYKTRTRGPTTYVSNLNLKTKDKPGKWILAGVALLLQ 4495
            |::|.||||||..||| |||...|||||:.|.||:|||||||||
Human  4458 RSVYSCPVYKTSQRGP-TYVWTFNLKTKENPSKWVLAGVALLLQ 4500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc93AB	NP_001262793.1	DHC_N1	204..782	CDD:285571	193/579 (33%)
		DHC_N2	1295..1708	CDD:285579	245/413 (59%)
		P-loop_NTPase	1841..2071	CDD:304359	206/229 (90%)
		P-loop_NTPase	2155..2290	CDD:304359	107/134 (80%)
		P-loop_NTPase	2448..2720	CDD:304359	171/272 (63%)
		P-loop_NTPase	2797..3064	CDD:304359	181/266 (68%)
		MT	3076..3419	CDD:289543	247/342 (72%)
		AAA_9	3447..3659	CDD:289547	158/211 (75%)
		Dynein_heavy	3799..4486	CDD:281078	475/701 (68%)
DNAH9	XP_011522005.1	DHC_N1	212..789	CDD:285571	193/580 (33%)
		DHC_N2	1295..1699	CDD:285579	245/413 (59%)
		P-loop_NTPase	1832..2062	CDD:304359	206/229 (90%)
		P-loop_NTPase	2146..2281	CDD:304359	107/134 (80%)
		AAA_7	2439..2710	CDD:289541	171/272 (63%)
		AAA_8	2788..3055	CDD:289546	181/266 (68%)
		MT	3067..3410	CDD:289543	247/342 (72%)
		AAA_9	3438..3650	CDD:289547	158/211 (75%)
		Dynein_heavy	3790..4491	CDD:281078	475/701 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159429
Domainoid	1	1.000	580	1.000	Domainoid score	I215
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20357
Inparanoid	1	1.050	4993	1.000	Inparanoid score	I2
Isobase	1	0.950	-	0	Normalized mean entropy	S2847
OMA	1	1.010	-	-		QHG56441
OrthoDB	1	1.010	-	-		D1463at33208
OrthoFinder	1	1.000	-	-		FOG0000396
OrthoInspector	1	1.000	-	-		otm42247
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	O	PTHR10676
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10120
SonicParanoid	1	1.000	-	-		X4281
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.750