Protein Alignment Rlip and ARHGAP25

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_016860912.1
• Gene: ARHGAP25 / 9938
• HGNCID: 28951
• Length: 650
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 110/489 - (22%)
• Similarity: 186/489 - (38%)
• Gaps: 126/489 - (25%)

  Fly   206 IPLVVRDCIDFLQDHLKCEQ-IYKIEPIKTRLMHFKRLYNNREHDSAVDELNLPTACSLLKLFLR 269
            :|::|..|.:|:.:|.:.|: |:::......:...:..::..|..|...:.::.|..|||||:||
Human   181 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR 245

  Fly   270 ELPEPLLTTDLVARF---EEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERH 331
            :||||::.......|   .::.:..:...|| ||.:.|..||:.|.:||:::......:......
Human   246 DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQ-ELMKQLSILPRDNYSLLSYICRFLHEIQLNCAV 309

  Fly   332 NKLNAQSLAMLLSPTLQMS---------------HRLMVALLCHCNNLFADVQLIKYVPPLTSTS 381
            ||::..:||.::...|..|               .|:|..::.....||...:.|...||.....
Human   310 NKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKND 374

  Fly   382 PKLP---------DTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREEQL--------------- 422
            ||..         |..||::  :.:.|| .|.:.|:.:....|.::....
Human   375 PKKAPVARSSVGWDATEDLR--ISRTDS-FSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGD 436

  Fly   423 WEVQ---RIITQLKRK---LRTFEKKQEKTAEEVDNSSSAPPAVA----------SED------- 464
            |::|   |..|...||   ...|:.......|...|...:|.:.|          |:|
Human   437 WKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDS 501

  Fly   465 ----TTDSKPA--GTPAVSTNNSISQE-EPKTDTLTPKDAPNDFTIDPSTGFILLPKSNPHRENL 522
                |.|:.|:  |:|....:...||. :.|.|||.   :||..| .|.       |.|...|
Human   502 QRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLA---SPNSET-GPG-------KKNSGEE-- 553

  Fly   523 LRLQIEYDELMEWQNELKARIVAERNEVYRLKQLYEQQSINSQMASLASGSQAPPESDYERIIEH 587
                 |.|.|.....||       |.|:...||:||:|                        |::
Human   554 -----EIDSLQRMVQEL-------RKEIETQKQMYEEQ------------------------IKN 582

  Fly   588 YTRENALLEHKKNMLGMELKEERRACIALQVELR 621
            ..:||..:..|...|..||::|::...||::.||
Human   583 LEKENYDVWAKVVRLNEELEKEKKKSAALEISLR 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	42/180 (23%)
ARHGAP25	XP_016860912.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910